The purpose of the current SNRP U54 program is to fortify emerging research programs in Neuroscience that advance the mission of NINDS. In the current application, this is done by dedicating funds to support three exploratory research projects (proposed in Element I) but also to Insure the success of faculty and students within the Neuroscience Institute in developing their individual research careers with the ultimate goal of achieving consistently funded, investigator-Initiated neuroscience research. Whenever possible, this will be accomplished by fulfilling an equally important goal of promoting diversity in the neuroscience workforce. Below, we outline our plan for supporting individual investigators and students to meet these goals. The MSM Neuroscience Institute currently consists of a good mix of senior and junior faculty. Currently, our senior faculty is composed of 7 full professors and 5 associate professors. Of these faculty, 7 have been recruited from other institutions at the associate professor level or higher, while 4 have been promoted within the institution after being recruited at the assistant professor level. This healthy mix gives enables us to have a wide variety of experiences on the hardships of progressing through an academic research career, as well as the unique problems associated with faculty development within our own Institution. This diversity in experience, along with the fad that we all work

National Institute of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZNS1-SRB-N (03))
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Morehouse School of Medicine
United States
Zip Code
Jiang, Nan; Wu, Junjun; Leng, Tiandong et al. (2017) Region specific contribution of ASIC2 to acidosis-and ischemia-induced neuronal injury. J Cereb Blood Flow Metab 37:528-540
Hardy, Jimmaline J; Mooney, Scott R; Pearson, Andrea N et al. (2017) Assessing the accuracy of blood RNA profiles to identify patients with post-concussion syndrome: A pilot study in a military patient population. PLoS One 12:e0183113
Liu, Mingli; Inoue, Koichi; Leng, Tiandong et al. (2017) ASIC1 promotes differentiation of neuroblastoma by negatively regulating Notch signaling pathway. Oncotarget 8:8283-8293
Hernandez-Encarnacion, Luisa; Sharma, Pankaj; Simon, Roger et al. (2017) Condition-specific transcriptional regulation of neuronal ion channel genes in brain ischemia. Int J Physiol Pathophysiol Pharmacol 9:192-201
Sánchez-Bretaño, Aída; Baba, Kenkichi; Janjua, Uzair et al. (2017) Melatonin partially protects 661W cells from H2O2-induced death by inhibiting Fas/FasL-caspase-3. Mol Vis 23:844-852
Laurent, Virgine; Sengupta, Anamika; Sánchez-Bretaño, Aída et al. (2017) Melatonin signaling affects the timing in the daily rhythm of phagocytic activity by the retinal pigment epithelium. Exp Eye Res 165:90-95
Hughes, Michael E; Abruzzi, Katherine C; Allada, Ravi et al. (2017) Guidelines for Genome-Scale Analysis of Biological Rhythms. J Biol Rhythms 32:380-393
Leng, Tiandong; Lin, Suizhen; Xiong, Zhigang et al. (2017) Lidocaine suppresses glioma cell proliferation by inhibiting TRPM7 channels. Int J Physiol Pathophysiol Pharmacol 9:8-15
Brager, Allison J; Heemstra, Lydia; Bhambra, Raman et al. (2017) Homeostatic effects of exercise and sleep on metabolic processes in mice with an overexpressed skeletal muscle clock. Biochimie 132:161-165
Ehlen, J Christopher; Brager, Allison J; Baggs, Julie et al. (2017) Bmal1 function in skeletal muscle regulates sleep. Elife 6:

Showing the most recent 10 out of 45 publications