ADMINISTRATIVE UNIT The Administrative Unit is responsible for coordinating and supporting all activities of the CREATE Consortium, to enable this RDCRC to achieve its scientific, educational and community engagement goals. The Administrative Unit will build on the existing infrastructure of five clinical centers of excellence for the diagnosis and treatment of patients with ALS and related disorders (Miami, Mayo, Kansas, UCSF and UCSD), the resources available through Clinical Translational Science Awards (CTSAs) at each of these institutions, the expertise and considerable genomic and bioinformatics expertise of our members (Miami, St. Jude, Mayo), our long history of collaboration with a diverse array of relevant patient advocacy groups (PAGs), and our engaged commitment to patient education, outreach and advocacy. We have also established new partnerships with the National ALS Registry (USA), the Ontario Neurodegenerative Research Initiative (Canada) and the STRENGTH Consortium (Europe) to form an international alliance with the collective resources to meaningfully impact ALS and related disorder research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
1U54NS092091-01
Application #
8929492
Study Section
Special Emphasis Panel (ZTR1-CI-8 (01))
Program Officer
Gubitz, Amelie
Project Start
2014-09-30
Project End
Budget Start
2014-09-30
Budget End
2015-06-30
Support Year
1
Fiscal Year
2014
Total Cost
$281,350
Indirect Cost
$98,060
Name
University of Miami School of Medicine
Department
Type
DUNS #
052780918
City
Coral Gables
State
FL
Country
United States
Zip Code
33146
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DeJesus-Hernandez, Mariely; Finch, NiCole A; Wang, Xue et al. (2017) In-depth clinico-pathological examination of RNA foci in a large cohort of C9ORF72 expansion carriers. Acta Neuropathol 134:255-269
Gendron, Tania F; Chew, Jeannie; Stankowski, Jeannette N et al. (2017) Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis. Sci Transl Med 9:

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