The Collaborative Research Core (CR) is specifically designed to be a gateway for non-NEIDL investigators who wish to establish a collaboration that would allow them to utilize NEIDL facilities and capacities to further their research programs. The principle requirements are that all proposed research is relevant to the mission of the NEIDL, represents a scientific collaboration between the outside investigators and NEIDL research staff, and is externally funded. For example, research collaborations can be developed with investigators within the network of Regional Centers of Excellence for Biodefense and Emerging Infectious Diseases Research (RCEs), or from the Regional Biodefense Laboratory when the special facilities of NEIDL can be usefully applied. CR is the unit within NEIDL interfacing with private and public sector researchers when NEIDL can add value to their research programs, as well as with international research organizations, such as the Indian Council for Medical Research. The CR Core would be the first unit at NEIDL to respond to new and rapidly emerging challenges anywhere in the world, to safely and securely study basic pathogenesis of newly emerging infectious agents in order to identify target molecules for diagnostics, therapeutic drugs, or vaccine candidates. The CR Core is therefore central to achieving the mission and goals of the NEIDL.

Public Health Relevance

The Core continues to be both pro-active and responsive to inquiries from research groups outside of NEIDL and Boston University, to develop new research projects that further the research mission of NEIDL. CR Core staff are prepared to rapidly develop partnerships and smooth the way for the research project to be approved within NEIDL and Boston University, as well as with the Boston Public Health Commission. India, and the Indian Council for Medical Research, is an excellent example of this outreach. We have initiated a BSL-4 training collaboration with ICMR and plans are developing for research on tuberculosis and drug resistance. India is important because it will continue to be a hotspot for new infectious disease emergence, and it has the necessary existing research capacity to effectively collaborate with NEIDL researchers. Similar connections will be developed with research institutions in Africa and Latin America over time. Since product development is the forte of the private pharma sector, we will also pursue potential research relationships with major biotech and bioPharma companies in order to be prepared to seamlessly and rapidly move discovery to product development.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Biocontainment Laboratory Operation Cooperative Agreement (UC7)
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Special Emphasis Panel (ZAI1-RCG-M (M1))
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Boston University
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LeDuc, James W; Anderson, Kevin; Bloom, Marshall E et al. (2009) Potential impact of a 2-person security rule on BioSafety Level 4 laboratory workers. Emerg Infect Dis 15:e1