The Eunice Kennedy Shriver National Institute of Child Health and Human Development's Neonatal Research Network is a cooperative group of academic centers that perform multicenter clinical trials to investigate problems in neonatal medicine, particularly those related to low birth weight, prematurity, and common neonatal medical problems. The Indiana University School of Medicine is the largest medical school and the site of the only comprehensive children's hospital in Indiana, a state with a population of 6.6 million and 83,000 annual births. Located at the geographical center of the state in Indianapolis, the Indiana University Medical Center serves as the principal referral center for high-risk perinatal patients and critically ill neonates. The clinical, teaching and research programs of the Section of Neonatal-Perinatal Medicine have a long tradition of excellence. Specific areas of expertise include clinical trials, fetal and neonatal nutrition, developmental hematopoiesis, molecular immunology, and stem cell biology. Since 1991, the Section of Neonatal-Perinatal Medicine at Indiana University has had continuous funding and has made significant contributions to the Neonatal Research Network because of the significant patient population available for studies, state-of-the-art clinical and research facilities, clinical research infrastructure, strong investigators with extensive clinical research expertise, and excellent research support staff. During the next funding cycle, Indiana University will continue to contribute a large number of subjects to all observational studies and clinical trials conducted by the Neonatal Research Network and will contribute to the scientific mission through development of innovative research protocols designed to address important clinical questions.

Public Health Relevance

The Neonatal Research Network's group of collaborative academic medical centers has advanced the field of neonatal medicine by conducting observation and investigational studies to improve patient care and the outcome of infants where little or no prior evidence was available for clinical decision-making.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Clinical Research Cooperative Agreements - Single Project (UG1)
Project #
5UG1HD027856-27
Application #
9249640
Study Section
Special Emphasis Panel (ZHD1-DSR-A (50)R)
Program Officer
Raju, Tonse N
Project Start
1991-04-01
Project End
2018-03-31
Budget Start
2017-04-01
Budget End
2018-03-31
Support Year
27
Fiscal Year
2017
Total Cost
$7,020
Indirect Cost
$2,520
Name
Indiana University-Purdue University at Indianapolis
Department
Pediatrics
Type
Schools of Medicine
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Autmizguine, Julie; Tan, Sylvia; Cohen-Wolkowiez, Michael et al. (2018) Antifungal Susceptibility and Clinical Outcome in Neonatal Candidiasis. Pediatr Infect Dis J 37:923-929
Meyers, J M; Tan, S; Bell, E F et al. (2018) Neurodevelopmental outcomes among extremely premature infants with linear growth restriction. J Perinatol :
Phelps, Dale L; Watterberg, Kristi L; Nolen, Tracy L et al. (2018) Effects of Myo-inositol on Type 1 Retinopathy of Prematurity Among Preterm Infants <28 Weeks' Gestational Age: A Randomized Clinical Trial. JAMA 320:1649-1658
Shankaran, Seetha; Laptook, Abbot R; McDonald, Scott A et al. (2017) Acute Perinatal Sentinel Events, Neonatal Brain Injury Pattern, and Outcome of Infants Undergoing a Trial of Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy. J Pediatr 180:275-278.e2
Denson, Lee A; McDonald, Scott A; Das, Abhik et al. (2017) Early Elevation in Interleukin-6 is Associated with Reduced Growth in Extremely Low Birth Weight Infants. Am J Perinatol 34:240-247
Boghossian, Nansi S; Hansen, Nellie I; Bell, Edward F et al. (2016) Outcomes of Extremely Preterm Infants Born to Insulin-Dependent Diabetic Mothers. Pediatrics 137:
Pedroza, Claudia; Tyson, Jon E; Das, Abhik et al. (2016) Advantages of Bayesian monitoring methods in deciding whether and when to stop a clinical trial: an example of a neonatal cooling trial. Trials 17:335
Phelps, Dale L; Ward, Robert M; Williams, Rick L et al. (2016) Safety and pharmacokinetics of multiple dose myo-inositol in preterm infants. Pediatr Res 80:209-17
Mirza, Hussnain; Laptook, Abbot R; Oh, William et al. (2016) Effects of indomethacin prophylaxis timing on intraventricular haemorrhage and patent ductus arteriosus in extremely low birth weight infants. Arch Dis Child Fetal Neonatal Ed 101:F418-22
Weissman, Scott J; Hansen, Nellie I; Zaterka-Baxter, Kristen et al. (2016) Emergence of Antibiotic Resistance-Associated Clones Among Escherichia coli Recovered From Newborns With Early-Onset Sepsis and Meningitis in the United States, 2008-2009. J Pediatric Infect Dis Soc 5:269-76

Showing the most recent 10 out of 20 publications