The Hospital for Sick Children (SickKids), in Toronto Canada, is one of the largest children?s hospitals in North America, with a world-renowned program in heart diseases in children. The SickKids Labatt Family Heart Center is a leader in research in heart disease in many areas; especially in large research studies that require the high recruitment of specialized patient populations. SickKids has been an active and productive member of a group of child heart disease research centers called the Pediatric Heart Network (PHN) since its inception 15 years ago. SickKids is an excellent team member for this network in terms of recruitment of patients and getting high quality results. SickKids members have greatly contributed to the PHN?s research into congenital heart disease and acquired heart disease, and now will lead one of the studies. It has many special features that help it to contribute to the studies, and also some special new initiatives that can help the network to move in new directions.

Public Health Relevance

The Hospital for Sick Children (SickKids) in Toronto, Canada, is one of the largest children?s hospitals in North America, with a world-renowned program in heart diseases in children. SickKids became a member of the Pediatric Heart Network (PHN) 15 years ago and has greatly contributed to the PHN?s research program and mentorship of new investigators. With SickKids? drive for innovation, expertise, facilities and resources, and strong track record of productivity and leadership in multi-institutional studies, the PHN is able to successfully carry out their clinical research programs so that children with heart disease can receive high-quality, evidence-based care.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Research Cooperative Agreements - Single Project (UG1)
Project #
5UG1HL135680-03
Application #
9619088
Study Section
Special Emphasis Panel (ZHL1)
Program Officer
Pemberton, Victoria
Project Start
2017-01-01
Project End
2023-12-31
Budget Start
2019-01-01
Budget End
2019-12-31
Support Year
3
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Hospital for Sick Chldrn (Toronto)
Department
Type
DUNS #
208511808
City
Toronto
State
ON
Country
Canada
Zip Code
M5 1X8
Burch, Phillip T; Ravishankar, Chitra; Newburger, Jane W et al. (2017) Assessment of Growth 6 Years after the Norwood Procedure. J Pediatr 180:270-274.e6
Atz, Andrew M; Zak, Victor; Mahony, Lynn et al. (2017) Longitudinal Outcomes of Patients With Single Ventricle After the Fontan Procedure. J Am Coll Cardiol 69:2735-2744
Ramroop, Ronand; Manase, George; Lu, Danny et al. (2017) Adrenergic receptor genotypes influence postoperative outcomes in infants in the Single-Ventricle Reconstruction Trial. J Thorac Cardiovasc Surg 154:1703-1710.e3
Meza, James M; Hickey, Edward J; Blackstone, Eugene H et al. (2017) The Optimal Timing of Stage 2 Palliation for Hypoplastic Left Heart Syndrome: An Analysis of the Pediatric Heart Network Single Ventricle Reconstruction Trial Public Data Set. Circulation 136:1737-1748
Goldberg, David J; Zak, Victor; Goldstein, Bryan H et al. (2017) Results of a phase I/II multi-center investigation of udenafil in adolescents after fontan palliation. Am Heart J 188:42-52