The Hopkins Lupus Cohort is a longitudinal study of over 2,300 SLE patients followed every 3 months by protocol. Through our collaborative effort and partnership with different institutions and by supplying patient samples, we will help answers many unanswered questions. Identifying the biological pathways of renal progression could result in targeted therapeutics. Our partnership would also help in identifying genes or gene signatures associated with SLE disease activity or related organ damage could elucidate the pathways by which pathology occurs and result in targeted treatments offered to the correct subset of patients. Also, by Identifying pathways that lead to flares in disease can be used to develop therapeutics to prevent flares.

Public Health Relevance

The Hopkins Lupus Cohort is a longitudinal study of over 2,300 SLE patients followed every 3 months by protocol. As a member of the partnership, our broad aim will be to contribute specimens, patient data, clinical and epidemiologic expertise, and creative ideas to support the collaborative work.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Exploratory/Developmental Cooperative Agreement Phase I (UH2)
Project #
1UH2AR067679-01
Application #
8851004
Study Section
Special Emphasis Panel (ZAR1-KM (M1))
Program Officer
Serrate-Sztein, Susana
Project Start
2014-09-24
Project End
2016-05-31
Budget Start
2014-09-24
Budget End
2015-05-31
Support Year
1
Fiscal Year
2014
Total Cost
$200,001
Indirect Cost
$73,190
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218