Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Exploratory/Developmental Cooperative Agreement Phase I (UH2)
Project #
4UH2HL123610-03
Application #
9308308
Study Section
Special Emphasis Panel (ZHL1-CSR-A (M1))
Program Officer
Twery, Michael
Project Start
Project End
Budget Start
2016-08-01
Budget End
2017-06-30
Support Year
3
Fiscal Year
2016
Total Cost
$101,710
Indirect Cost
$42,918
Name
University of Chicago
Department
Type
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Prabhakar, Nanduri R; Peng, Ying-Jie; Yuan, Guoxiang et al. (2018) Reactive oxygen radicals and gaseous transmitters in carotid body activation by intermittent hypoxia. Cell Tissue Res 372:427-431
Bhattacharjee, Abir; Sinha, Antara; Ratia, Kiira et al. (2017) 2-Arylidene Hydrazinecarbodithioates as Potent, Selective Inhibitors of Cystathionine ?-Lyase (CSE). ACS Med Chem Lett 8:1241-1245
Nanduri, Jayasri; Peng, Ying-Jie; Wang, Ning et al. (2017) Epigenetic regulation of redox state mediates persistent cardiorespiratory abnormalities after long-term intermittent hypoxia. J Physiol 595:63-77
Yao, Yao; Kong, Chen; Yin, Liang et al. (2017) Time-Gated Detection of Cystathionine ?-Lyase Activity and Inhibition with a Selective, Luminogenic Hydrogen Sulfide Sensor. Chemistry 23:752-756
Prabhakar, Nanduri R; Peng, Ying-Jie (2017) Oxygen Sensing by the Carotid Body: Past and Present. Adv Exp Med Biol 977:3-8
Yuan, Guoxiang; Peng, Ying-Jie; Khan, Shakil A et al. (2016) H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea. Sci Signal 9:ra80
Prabhakar, Nanduri R; Semenza, Gregg L (2016) Regulation of carotid body oxygen sensing by hypoxia-inducible factors. Pflugers Arch 468:71-5
Prabhakar, Nanduri R (2016) Carotid body chemoreflex: a driver of autonomic abnormalities in sleep apnoea. Exp Physiol 101:975-85
Prabhakar, Nanduri R; Peng, Ying-Jie; Kumar, Ganesh K et al. (2015) Peripheral chemoreception and arterial pressure responses to intermittent hypoxia. Compr Physiol 5:561-77
Nanduri, Jayasri; Prabhakar, Nanduri R (2015) Epigenetic Regulation of Carotid Body Oxygen Sensing: Clinical Implications. Adv Exp Med Biol 860:1-8

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