This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. We have established the University of Massachusetts Center for Clinical and Translational Science (UMCCTS) which includes the five UMass campuses. Operationally, the Center is located at the University's Worcester campus and managed by the School of Medicine. The Center serves as the """"""""academic home"""""""" for clinical and translational scientists across all UMass campuses. The CTSA program will build clinical and translational research upon a foundation of world class basic science as evidenced by the award of the Nobel Prize in Physiology or Medicine to Craig Mello in 2006 and the Albert Lasker Award to Victor Ambros in 2008. The UMCCTS aims are to: 1) Accelerate early phase translational (Tl) studies by recruiting outstanding T1 research leaders;establishing innovative research core facilities;and developing new therapies, devices, and interventions based upon UMass discoveries;2) Integrate unique networks of clinical research and healthcare delivery in Central New England and Massachusetts at-large to build and expand T2 (clinical effectiveness research) and T3 (implementation and dissemination research) capacity by recruiting outstanding T2 and T3 research leaders, and by developing innovative T2/T3 core facilities;and enhancing patient and community outreach and participation in clinical/population-based research;3) The UMCCTS will work collaboratively with all campuses and schools ofthe UMass system in developing programs, curricula, and faculty support systems that promote careers in clinical and translational research. Governor Deval Patrick and the Massachusetts Legislature recently enacted legislation committing $1 billion in state investment to be directed to the Life Sciences in the Commonwealth. With $90 million in seed funding, the University has established the UMass Advanced Therapeutics Cluster (UMATC) which includes the RNA Therapeutics Institute, the Center for Stem Cell Biology and Regenerative Medicine, and the Gene Therapy Center. The UMATC joins the Massachusetts Biologic Laboratories, Meyers Primary Care Institute, and Commonwealth Medicine, four innovative components that are rarely found in academic centers, to speed bench to bedside to community discoveries in clinical and translational research.

Public Health Relevance

The University of Massachusetts Center for Clinical and Translational Science (UMCCTS) will transform the conduct of clinical and translational research by providing an """"""""academic home"""""""" for all university clinical investigators. The UMCCTS will provide robust pilot grant programs, comprehensive education and career development programs, and innovative core facilities to support and nurture clinical investigators.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
5UL1RR031982-02
Application #
8365149
Study Section
Special Emphasis Panel (ZRR1-CR-1 (01))
Project Start
2011-04-01
Project End
2012-03-31
Budget Start
2011-04-01
Budget End
2012-03-31
Support Year
2
Fiscal Year
2011
Total Cost
$2,540,582
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Type
Other Domestic Higher Education
DUNS #
603847393
City
Worcester
State
MA
Country
United States
Zip Code
01655
Fang, Hua (2017) MIFuzzy Clustering for Incomplete Longitudinal Data in Smart Health. Smart Health (Amst) 1-2:50-65
Blok, Amanda C; May, Christine N; Sadasivam, Rajani S et al. (2017) Virtual Patient Technology: Engaging Primary Care in Quality Improvement Innovations. JMIR Med Educ 3:e3
Chang, Bei-Hung; Hoaglin, David C (2017) Meta-Analysis of Odds Ratios: Current Good Practices. Med Care 55:328-335
Wang, Jin; Fang, Hua; Carreiro, Stephanie et al. (2017) A New Mining Method to Detect Real Time Substance Use Events from Wearable Biosensor Data Stream. Int Conf Comput Netw Commun 2017:465-470
Nobrega, Suzanne; Champagne, Nicole; Abreu, Marlene et al. (2016) Obesity/Overweight and the Role of Working Conditions: A Qualitative, Participatory Investigation. Health Promot Pract 17:127-36
Shaw, Joshua J; Psoinos, Charles M; Santry, Heena P (2016) It's All About Location, Location, Location: A New Perspective on Trauma Transport. Ann Surg 263:413-8
Zhang, Zhaoyang; Fang, Hua; Wang, Honggang (2016) Multiple Imputation based Clustering Validation (MIV) for Big Longitudinal Trial Data with Missing Values in eHealth. J Med Syst 40:146
Zhang, Zhaoyang; Fang, Hua (2016) Multiple- vs Non- or Single-Imputation based Fuzzy Clustering for Incomplete Longitudinal Behavioral Intervention Data. IEEE Int Conf Connect Health Appl Syst Eng Technol 2016:219-228
Wang, Chanpaul Jin; Fang, Hua; Wang, Honggang (2016) ESammon: A Computationaly Enhanced Sammon Mapping based on Data Density. Int Conf Comput Netw Commun 2016:
Bova, Carol; Nnaji, Chioma; Woyah, Augustus et al. (2016) HIV Stigma, Testing Attitudes and Health Care Access Among African-Born Men Living in the United States. J Immigr Minor Health 18:187-93

Showing the most recent 10 out of 105 publications