The University of Texas Health Science Center at San Antonio (UTHSCSA) has established the Institute for Integration of Medicine and Science (IIMS) as the home for our Clinical and Translational Science Award [CTSA). Our mission is to achieve optimal integration of clinical and translational research, education, training, and career development across all UTHSCSA schools and among our partner organizations in the South Texas region. IIMS will focus existing and newly developing resources and intellectual capital on advancing the discipline of clinical and translational research for the improvement of human health. Meaningful bidirectional community participation has promoted buy-in from all stakeholders and will remain a key principle as IIMS continues to evolve. IIMS partners have brought together major talent and a broad array of resources to create synergies that add value to all participating organizations, residents of our region and the CTSA network. Key function working groups have developed many innovative approaches to providing optimal support for IIMS investigators and programs. Distinctive features of IIMS include: 1) thriving partnerships with key public and private organizations (academic, health care, public health, military), 2) major investments in research resources and infrastructure, 3) the largest cadre of military health care and biomedical research operations in the US, 4) one of the world's largest primate research colonies, 5) a 46,000 square mile service area populated by predominantly Hispanic residents comprising some of the country's poorest people, plagued by high rates of health disparities, providing an opportunity, challenge and obligation for us to make a significant impact on human health. Within the context of our collective resources, community focus, and unique regional demographics, we have identified four Specific Aims as the core elements of our CTSA application:
Aim 1 - To support transformative clinical and translational research by providing a comprehensive infrastructure integrated effectively among our partners for the creation of multidisciplinary clinical research teams;
Aim 2 - To create the optimal intellectual environment and nurturing atmosphere necessary for the training of future clinical and translational career investigators, building upon existing strengths, partnerships, a diverse trainee pool and strong faculty dedication to mentoring;
Aim 3 - To develop community-based models that address the best means for translating research findings, focusing on our unique population-specific risk factors, disease burdens and health disparities;
Aim 4 - To implement robust tracking and outcome evaluation systems across all IIMS programs. The mission of IIMS is sharply focused on public health. Indeed, our primary vision is to work closely with all partners to translate the results of our academic and community-based research for the direct benefit of our regional population.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
8UL1TR000149-05
Application #
8285100
Study Section
Special Emphasis Panel (ZRR1-SRC (99))
Program Officer
Sawczuk, Andrea
Project Start
2008-05-19
Project End
2013-10-31
Budget Start
2012-05-01
Budget End
2013-10-31
Support Year
5
Fiscal Year
2012
Total Cost
$4,737,354
Indirect Cost
$1,264,314
Name
University of Texas Health Science Center San Antonio
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Talley Watts, Lora; Long, Justin Alexander; Boggs, Robert Cole et al. (2016) Delayed Methylene Blue Improves Lesion Volume, Multi-Parametric Quantitative Magnetic Resonance Imaging Measurements, and Behavioral Outcome after Traumatic Brain Injury. J Neurotrauma 33:194-202
Green, Dustin; Ruparel, Shivani; Gao, Xiaoli et al. (2016) Central activation of TRPV1 and TRPA1 by novel endogenous agonists contributes to mechanical allodynia and thermal hyperalgesia after burn injury. Mol Pain 12:
Perkins, Susan M; Bacchetti, Peter; Davey, Cynthia S et al. (2016) Best Practices for Biostatistical Consultation and Collaboration in Academic Health Centers. Am Stat 70:187-194
Ma, Chifeng; Sastry, Konduru S; Flore, Mario et al. (2016) CrossLink: a novel method for cross-condition classification of cancer subtypes. BMC Genomics 17 Suppl 7:549
Broadus, Matthew R; Yew, P Renee; Hann, Stephen R et al. (2015) Small-molecule high-throughput screening utilizing Xenopus egg extract. Methods Mol Biol 1263:63-73
Mazumdar, Madhu; Messinger, Shari; Finkelstein, Dianne M et al. (2015) Evaluating Academic Scientists Collaborating in Team-Based Research: A Proposed Framework. Acad Med 90:1302-8
Long, Justin A; Watts, Lora T; Li, Wei et al. (2015) The effects of perturbed cerebral blood flow and cerebrovascular reactivity on structural MRI and behavioral readouts in mild traumatic brain injury. J Cereb Blood Flow Metab 35:1852-61
Parra-Medina, Deborah; Mojica, Cynthia; Liang, Yuanyuan et al. (2015) Promoting Weight Maintenance among Overweight and Obese Hispanic Children in a Rural Practice. Child Obes 11:355-63
Overholser, Stephen; Nielsen, Matthew; Torkko, Kathleen et al. (2015) Active Surveillance is an Appropriate Management Strategy for a Proportion of Men Diagnosed with Prostate Cancer by Prostate Specific Antigen Testing. J Urol 194:680-4
Long, Justin Alexander; Watts, Lora Talley; Chemello, Jonathan et al. (2015) Multiparametric and longitudinal MRI characterization of mild traumatic brain injury in rats. J Neurotrauma 32:598-607

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