One of medicine's greatest challenges today is the efficient, seamless translation of biomedical research discoveries into clinical applications. New methodologies, technologies and integrated information systems offer unprecedented promise for discovery and growth. Yet, significant barriers confound our ability to atract essential knowledge from these burgeoning research platforms. The University of Colorado at Denver and Health Sciences Center (UCDHSC) and our Affiliates (6 major hospitals and health care nstitutions serving our region, the University of Colorado at Boulder, and local communities) are committed to transforming our aligned enterprise to meet these challenges. In response to the NIH Roadmap Initiative RM-07-007, UCDHSC and Affiliates are creating the Colorado Clinical and Translational Sciences Institute (CCTSI). This transformation will be achieved, with substantial institutional support, through 4 Specific Goals: ^Transformation of the Institution: The CCTSI will be the integrated and interdisciplinary statewide academic home for the disciplines of clinical and translational sciences and research. 2) Transformation of the Clinical and Translational Scientist: The CCTSI will enhance, integrate and transform training of translational scientists, to develop a new generation of investigators with advanced degrees, interdisciplinary and collaborative skills and a team approach to scientific investigation. 3) Transformation of Discovery Translational Research: The CCTSI will transform the performance of bench-to-beside research by providing new resources and infrastructure, integrating current and developing new innovative research tools and methodologies, catalyzing new interdisciplinary research programs, and removing barriers to efficiency. 4) Transformation of Community Translational Research and Practice: This will be peformed by enhancing, extending and integrating community-based participatory research into programs that will engage community participation and develop novel methodologies and informatics platforms for translation of discoveries into practice. Implicit to the success of these programs will be a rigorous ongoing self-evaluation to ensure the most productive use of resources. These programs will be centralized on the new Anschutz Medical Campus, constructed in its entirety over the last 10years, in which adjacencies of all Health Science Schools, research facilities and a biomedical corporate park create the ideal environment for success.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
8UL1TR000154-05
Application #
8287017
Study Section
Special Emphasis Panel (ZRR1-SRC (99))
Program Officer
Purucker, Mary E
Project Start
2008-05-19
Project End
2013-10-31
Budget Start
2012-05-01
Budget End
2013-10-31
Support Year
5
Fiscal Year
2012
Total Cost
$14,386,567
Indirect Cost
$2,735,069
Name
University of Colorado Denver
Department
Pediatrics
Type
Schools of Medicine
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Pereira, Rocio I; Low Wang, Cecilia C; Wolfe, Pamela et al. (2016) Associations of Adiponectin with Adiposity, Insulin Sensitivity, and Diet in Young, Healthy, Mexican Americans and Non-Latino White Adults. Int J Environ Res Public Health 13:ijerph13010054
Yang, Aaron Jay; Brakke, Rachel A; Boimbo, Sandra et al. (2016) Residency and Beyond: Subspecialization Trends Among Graduating Physiatry Residents and the Musculoskeletal Curriculum. Am J Phys Med Rehabil 95:152-7
Carlton, Elizabeth J; Woster, Andrew P; DeWitt, Peter et al. (2016) A systematic review and meta-analysis of ambient temperature and diarrhoeal diseases. Int J Epidemiol 45:117-30
Dayton, Michael R; Judd, Dana L; Hogan, Craig A et al. (2016) Performance-Based Versus Self-Reported Outcomes Using the Hip Disability and Osteoarthritis Outcome Score After Total Hip Arthroplasty. Am J Phys Med Rehabil 95:132-8
Zoratti, Edward M; Krouse, Rebecca Z; Babineau, Denise C et al. (2016) Asthma phenotypes in inner-city children. J Allergy Clin Immunol 138:1016-1029
Martinez-Camacho, Alvaro; Fortune, Brett E; Gralla, Jane et al. (2016) Early weight changes after liver transplantation significantly impact patient and graft survival. Eur J Gastroenterol Hepatol 28:107-15
Grubenhoff, Joseph A; Currie, Dustin; Comstock, R Dawn et al. (2016) Psychological Factors Associated with Delayed Symptom Resolution in Children with Concussion. J Pediatr 174:27-32.e1
Yi-Frazier, Joyce P; Hilliard, Marisa E; Fino, Nora F et al. (2016) Whose quality of life is it anyway? Discrepancies between youth and parent health-related quality of life ratings in type 1 and type 2 diabetes. Qual Life Res 25:1113-21
Leigh, Margaret W; Ferkol, Thomas W; Davis, Stephanie D et al. (2016) Clinical Features and Associated Likelihood of Primary Ciliary Dyskinesia in Children and Adolescents. Ann Am Thorac Soc 13:1305-13
Dillon, Stephanie M; Lee, Eric J; Donovan, Andrew M et al. (2016) Enhancement of HIV-1 infection and intestinal CD4+ T cell depletion ex vivo by gut microbes altered during chronic HIV-1 infection. Retrovirology 13:5

Showing the most recent 10 out of 328 publications