The Institute of Translational Health Sciences (ITHS) is a collaboration between 3 partners;the University of Washington, the Fred Hutchinson Cancer Research Center, and Seattle Children's. Over the last 4 years, the work of the ITHS has also extended to partner institutions in the Puget Sound and throughout the 5-state region of Washington, Wyoming, Alaska, Montana, and Idaho. In 2007, we established the ITHS as a "collaboratory"- an academic home without walls for translational investigators in our region. The ITHS supports novel research resources in biomedical informatics, biostatistics, therapeutic product development and clinical research, supported by expertise in bioethics and regulatory practices. To train the next generation of researchers, the ITHS has developed multidisciplinary educational offerings in translational research: structured training programs (pre-doctoral and post-doctoral programs) and lifelong learning programs (flexible continuing education for researchers at any stage of their career). The ITHS has also established collaboration networks for research and engaged nearly 2000 members and users. ITHS memberships and networks have spanned across the 5-state region and diverse populations such as the Alaska Native/ American Indian communities to engage new groups in clinical and translational research. In the proposed funding period we will extend the collaboratory to multidisciplinary teams and focus on moving discoveries across the translational research continuum rapidly and efficiently. We will develop state-of-the-art methods and tools to transform research processes. Our overarching goals are to: 1) Develop and promote multidisciplinary teams and academic-community partnerships to increase the speed and quality of translational research, 2) Train scientists to cross the interface of translational research phases, so their ideas will move more quickly to a health impact, and 3) Transform research processes and practicesin our regions and the CTSA network through dissemination of innovative approaches and best practices.

Public Health Relevance

The health care needs of our nation are complex and finding effective solutions and cures will require a multi- disciplinary, multi-faceted approach based on innovation and state-of-the-art science. The CTSA program, both at the local level and through the national CTSA consortium, provides the elements needed to accelerate discoveries at the bench into tangible health benefits for our communities.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
5UL1TR000423-07
Application #
8499459
Study Section
Special Emphasis Panel (ZRR1-CR-1 (01))
Program Officer
Wilson, Todd
Project Start
2007-09-17
Project End
2017-05-31
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
7
Fiscal Year
2013
Total Cost
$9,035,117
Indirect Cost
$1,960,563
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Bentov, Itay; Damodarasamy, Mamatha; Spiekerman, Charles et al. (2016) Lidocaine Impairs Proliferative and Biosynthetic Functions of Aged Human Dermal Fibroblasts. Anesth Analg 123:616-23
Birgfeld, Craig B; Heike, Carrie L; Saltzman, Babette S et al. (2016) Reliable classification of facial phenotypic variation in craniofacial microsomia: a comparison of physical exam and photographs. Head Face Med 12:14
Chesley, Patrick M; Sanchez, Sabrina E; Melzer, Lilah et al. (2016) Neurodevelopmental and Cognitive Outcomes in Children With Intestinal Failure. J Pediatr Gastroenterol Nutr 63:41-5
Cole, Allison M; Stephens, Kari A; Keppel, Gina A et al. (2016) Extracting Electronic Health Record Data in a Practice-Based Research Network: Processes to Support Translational Research across Diverse Practice Organizations. EGEMS (Wash DC) 4:1206
Liang, C Jason; Heagerty, Patrick J (2016) A risk-based measure of time-varying prognostic discrimination for survival models. Biometrics :
Lee, Sandra Soo-Jin; Kelley, Maureen; Cho, Mildred K et al. (2016) Adrift in the Gray Zone: IRB Perspectives on Research in the Learning Health System. AJOB Empir Bioeth 7:125-134
Godfrey, Kathryn M; Strachan, Eric; Mostoufi, Sheeva et al. (2016) Familial Contributions to Self-Reported Sleep and Pain in Female Twins. Pain Med 17:33-9
Grady, Christine; Nogues, Isabella; Wiener, Lori et al. (2016) Adolescent Research Participants' Descriptions of Medical Research. AJOB Empir Bioeth 7:1-7
Yi-Frazier, Joyce P; Hilliard, Marisa E; Fino, Nora F et al. (2016) Whose quality of life is it anyway? Discrepancies between youth and parent health-related quality of life ratings in type 1 and type 2 diabetes. Qual Life Res 25:1113-21
Kemna, Mariska; Albers, Erin; Bradford, Miranda C et al. (2016) Impact of donor-recipient sex match on long-term survival after heart transplantation in children: An analysis of 5797 pediatric heart transplants. Pediatr Transplant 20:249-55

Showing the most recent 10 out of 330 publications