The Institute of Translational Health Sciences (ITHS) is a collaboration between 3 partners;the University of Washington, the Fred Hutchinson Cancer Research Center, and Seattle Children's. Over the last 4 years, the work of the ITHS has also extended to partner institutions in the Puget Sound and throughout the 5-state region of Washington, Wyoming, Alaska, Montana, and Idaho. In 2007, we established the ITHS as a """"""""collaboratory""""""""- an academic home without walls for translational investigators in our region. The ITHS supports novel research resources in biomedical informatics, biostatistics, therapeutic product development and clinical research, supported by expertise in bioethics and regulatory practices. To train the next generation of researchers, the ITHS has developed multidisciplinary educational offerings in translational research: structured training programs (pre-doctoral and post-doctoral programs) and lifelong learning programs (flexible continuing education for researchers at any stage of their career). The ITHS has also established collaboration networks for research and engaged nearly 2000 members and users. ITHS memberships and networks have spanned across the 5-state region and diverse populations such as the Alaska Native/ American Indian communities to engage new groups in clinical and translational research. In the proposed funding period we will extend the collaboratory to multidisciplinary teams and focus on moving discoveries across the translational research continuum rapidly and efficiently. We will develop state-of-the-art methods and tools to transform research processes. Our overarching goals are to: 1) Develop and promote multidisciplinary teams and academic-community partnerships to increase the speed and quality of translational research, 2) Train scientists to cross the interface of translational research phases, so their ideas will move more quickly to a health impact, and 3) Transform research processes and practicesin our regions and the CTSA network through dissemination of innovative approaches and best practices.

Public Health Relevance

The health care needs of our nation are complex and finding effective solutions and cures will require a multi- disciplinary, multi-faceted approach based on innovation and state-of-the-art science. The CTSA program, both at the local level and through the national CTSA consortium, provides the elements needed to accelerate discoveries at the bench into tangible health benefits for our communities.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
5UL1TR000423-07
Application #
8499459
Study Section
Special Emphasis Panel (ZRR1-CR-1 (01))
Program Officer
Wilson, Todd
Project Start
2007-09-17
Project End
2017-05-31
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
7
Fiscal Year
2013
Total Cost
$9,035,117
Indirect Cost
$1,960,563
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Peltan, Ithan D; Mitchell, Kristina H; Rudd, Kristina E et al. (2017) Physician Variation in Time to Antimicrobial Treatment for Septic Patients Presenting to the Emergency Department. Crit Care Med 45:1011-1018
Shah, Aalap C; Nair, Bala G; Spiekerman, Charles F et al. (2017) Continuous intraoperative epidural infusions affect recovery room length of stay and analgesic requirements: a single-center observational study. J Anesth 31:494-501
de Lacy, N; Doherty, D; King, B H et al. (2017) Disruption to control network function correlates with altered dynamic connectivity in the wider autism spectrum. Neuroimage Clin 15:513-524
Tuttle, Katherine R (2017) Back to the Future: Glomerular Hyperfiltration and the Diabetic Kidney. Diabetes 66:14-16
Fuentes, Molly M; Thompson, Leah; Quistberg, D Alex et al. (2017) Auditing Access to Outpatient Rehabilitation Services for Children With Traumatic Brain Injury and Public Insurance in Washington State. Arch Phys Med Rehabil 98:1763-1770.e7
Leung, Daniel H; Heltshe, Sonya L; Borowitz, Drucy et al. (2017) Effects of Diagnosis by Newborn Screening for Cystic Fibrosis on Weight and Length in the First Year of Life. JAMA Pediatr 171:546-554
Javid, Patrick J; Oron, Assaf P; Duggan, Christopher et al. (2017) The extent of intestinal failure-associated liver disease in patients referred for intestinal rehabilitation is associated with increased mortality: an analysis of the pediatric intestinal failure consortium database. J Pediatr Surg :
Low, Daniel; Merkel, Emily C; Menon, Manoj et al. (2017) Chemotherapy Use at the End of Life in Uganda. J Glob Oncol 3:711-719
LaCourse, Sylvia M; Cranmer, Lisa M; Matemo, Daniel et al. (2017) Effect of Pregnancy on Interferon Gamma Release Assay and Tuberculin Skin Test Detection of Latent TB Infection Among HIV-Infected Women in a High Burden Setting. J Acquir Immune Defic Syndr 75:128-136
Bogachus, Lindsey D; Oseid, Elizabeth; Bellin, Melena et al. (2017) Deficient Endogenous Glucose Production During Exercise After Total Pancreatectomy/Islet Autotransplantation. J Clin Endocrinol Metab 102:3288-3295

Showing the most recent 10 out of 433 publications