The Institute for Clinical and Translational Science (ICTS) was established to be an integrated home for clinical and translational science and training at the University of Iowa (UI) and to create a catalytic infrastructure for nurturing the broad (T1-T4) spectrum of translational science. Since our funding as a CTSA institution in September 2007, the ICTS has successfully leveraged NIH support with substantial UI investments ($19.1 million) to accomplish a number of milestones towards five overall goals;1) support an integrated and inclusive academic infrastructure for clinical and translational science that adds value to other UI research programs, 2) develop curricula and provide training opportunities in translational science that are tailored to the unique needs of outstanding scholars and research personnel from diverse disciplines and backgrounds, 3) leverage ICTS and institutional resources to provide a unique set of core services that support clinical and translational investigators and that diminish administrative and regulatory barriers, 4) foster new cross-disciplinary collaborations that lead to innovative methods in translational science, high impact research that advances understanding of disease prevention and treatment, and to a more rapid pipeline of products to improve health, and 5) nurture previously established community partnerships and disseminate and implement interventions that result in measurable improvements in health and wellbeing. Activities proposed for the next funding cycle will build on prior accomplishments and will be implemented through nine key functions, including: i) Research Education, Training, and Career Development;ii) Biomedical Informatics;iii) Biostatistics, Epidemiology, and Research Design, iv) Clinical Research Resources;v) Community Engagement;vi) Evaluation and Tracking;vii) Novel Clinical and Translational Methodologies;viii) Pilot Studies;and ix) Regulatory Knowledge and Support and Ethics. In addition to the nine key functions, activities will be driven by four cross-cutting Thematic Areas-Genetics, Genomics, and Biorepository Development, Child Health, Comparative Effectiveness Research, and Product Development- which will be responsible for managing activities that will be integrated into different key functions.

Public Health Relevance

This application will support the work of the University of Iowa Institute for Clinical and Translational Science to translate basic science discoveries into novel treatments and to develop partnerships with community organizations to disseminate best clinical practices that will improve healthcare delivery and population heath in the US. The application will also support the development of interdisciplinary educational programs to train the next generation of clinical and translational scientists.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
3UL1TR000442-06S1
Application #
8738809
Study Section
Special Emphasis Panel (ZRR1-CR-1 (01))
Program Officer
Rosenblum, Daniel
Project Start
2007-09-17
Project End
2014-04-30
Budget Start
2013-09-26
Budget End
2014-04-30
Support Year
6
Fiscal Year
2013
Total Cost
$4,086,648
Indirect Cost
$1,374,437
Name
University of Iowa
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
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