Applying for our second CTSA, Tufts Clinical and Translational Science Institute (CTSl) remains avidly committed to involving the full spectrum of clinical ahd translational research (CTR) to meet the pnsmise of biomedical science, not only bench to bedside (T1) translation, crucial to having health impact, translation into effective clinical practice (T2), care delivery and public health (TS), and health policy ('T4). In 2008 we started Tufts CTSl building on prior CTR resources, services, and educational programs, we purposely selected partners that would leverage and complement each other's special assets. Our 38 strategically- chosen partners Include 12 Tufts University schools/research centers, ten Tufts hospitals, three academic institutions (Brandeis University, Northeastern University, RAND Corporation), eight community-based organizations, and five industry partners, an outstanding and synergistic resources, opportunities, and education across the T1-T4 spectrum. Described in our application's four sections are four aims that build on this platform:
AIM 1 : Strengthen Tufts CTSl overall by: 1) organizing and leading its partners in their commitment to this shared home for CTR; 2) expanding efficient access for all partners to a full spectrum of high-quality resources in a way that promotes collaborative CTR across disciplines and institutionsjS) advancing the field of CTR through local and national leadership and development of novel methods;4) providing innovative and tai^eted education and training across the T1-4 spectmm. (Section I) AIM 2: Operationalize and implement the CTR home and its infra- stnjcture, sen/ices and programs, including its central office personnel, administrative and financial management systems, committees, and other necessary structures. (Section II) AIM 3: Sustain and grow innovative resources, services, and policies that support and promote collaborative, cross-disciplinary, full-spectrum translational research. (Section III) AIM 4: Develop and broaden the CTR workforce through education and training across the T1-T4 spectrum, with a specific focus on addressing translational gaps between bench to bedside and from bedside to widespread impact on health. (Section IV)

Public Health Relevance

(See Instmctions): Tufts Clinical and Translational Science Institute uses the entire spectrum of clinical and translational research (CTR) to help meet the promise and the public's needs of biomedical science.This includes bench to bedside (Tl) translation and crucially for having health impact, translation into effective clinical practice (T2), care delivery and public health (TS-), and health policy (?T4).

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
4UL1TR001064-04
Application #
9064892
Study Section
Special Emphasis Panel (ZAI1)
Program Officer
Wilde, David B
Project Start
2013-09-26
Project End
2018-04-30
Budget Start
2016-05-01
Budget End
2017-04-30
Support Year
4
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Tufts University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
039318308
City
Boston
State
MA
Country
United States
Zip Code
Leyenaar, JoAnna K; Rizzo, Paul A; Khodyakov, Dmitry et al. (2018) Importance and Feasibility of Transitional Care for Children With Medical Complexity: Results of a Multistakeholder Delphi Process. Acad Pediatr 18:94-101
Riley, Hayden; Headley, Samuel; Lindenauer, Peter K et al. (2018) Patient Perception of How Smoking Status Influences Cardiac Rehabilitation Attendance After an Acute Cardiac Hospitalization. J Cardiopulm Rehabil Prev :
Ng, Isaac; Bugaev, Nikolay; Riesenburger, Ron et al. (2018) The profile of blunt traumatic infratentorial cranial bleed types. J Clin Neurosci :
Lee, Augustine C; Harvey, William F; Price, Lori Lyn et al. (2018) Dose-Response Effects of Tai Chi and Physical Therapy Exercise Interventions in Symptomatic Knee Osteoarthritis. PM R 10:712-723
Hou, Xiaoli; Zhang, Yongzhao; Li, Wei et al. (2018) CDK6 inhibits white to beige fat transition by suppressing RUNX1. Nat Commun 9:1023
Kerrigan, Andrew; Kaonga, Nadi N; Tang, Alice M et al. (2018) Content guidance for mobile phones short message service (SMS)-based antiretroviral therapy adherence and appointment reminders: a review of the literature. AIDS Care :1-11
Leyenaar, JoAnna K; Rizzo, Paul A; O'Brien, Emily R et al. (2018) Paediatric hospital admission processes and outcomes: a qualitative study of parents' experiences and priorities. BMJ Qual Saf 27:790-798
Dungan, Kathleen; Craven, Timothy E; Soe, Kyaw et al. (2018) Influence of metabolic syndrome and race on the relationship between intensive blood pressure control and cardiovascular outcomes in the SPRINT cohort. Diabetes Obes Metab 20:629-637
Lee, Augustine C; Bloch, Rina M; Harvey, William F et al. (2018) Could Activity Modifications Indicate Physical Decline Among Adults With Symptomatic Knee Osteoarthritis? Am J Phys Med Rehabil 97:96-103
Pack, Quinn R; Bauldoff, Gerene; Lichtman, Steven W et al. (2018) Prioritization, Development, and Validation of American Association of Cardiovascular and Pulmonary Rehabilitation Performance Measures. J Cardiopulm Rehabil Prev 38:208-214

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