The Ohio State University created the Center for Clinical and Translational Science (CCTS) to catalyze research teams and facilitate innovation through creation of an environment that fosters translation of knowledge to improve human health. The Center will accomplish four specific aims: 1) Build on the unique and diverse strengths of our institution to create an integrated academic home for innovative, team-oriented clinical and translational science; 2) Enhance and nurture the career development of highly trained investigators, with an emphasis on innovation and transdisciplinary science; 3) Integrate and enhance an administrative infrastructure to optimize the efficient conduct of the highest quality, generalizable clinical and translational science that is relevant to the community setting; 4) Develop, enhance and integrate a portfolio of outstanding shared resources in support of transformative clinical and translational research. The CCTS will continue to focus on integrating the traditional biomedical research process (basic scientific discovery with translation to the bedside to dissemination into the community for improved patient outcomes) with a public health model (surveillance to prevention to response). By incorporating this bi-directional model in the creation of a robust translational science infrastructure, the OSU CCTS will foster both the traditional discovery to best practice paradigm as well as taking advantage of the insight garnered from our foundation of excellence in clinical care to stimulate basic discovery and clinical research inquiry. The vision and specific aims will be achieved through an integrated model of governance and partnership, home, and leadership for clinical and translational research spanning NCH and OSU; focused pilot funding initiatives for new team development within an innovation ecosystem; unique educational and training architecture which integrates acquisition of core competencies in research methodology, interpretation of results, implementation of findings, design thinking, team leadership skills and business acumen with rigorous discipline-specific laboratory (bench, clinical or community) training; and a clinical and translational science infrastructure that is cohesive, innovative and adaptable and more effective than the services that currently exist in order to ensure provision of the full range of disease-agnostic scientific resources needed to traverse the continuum of research from T1-4.
(See Instructions): The Center for Clinical and Translational Science will improve human health by bringing the benefits of science more quickly into patient care.
|Veronese, Nicola; Stubbs, Brendon; Noale, Marianna et al. (2017) Adherence to a Mediterranean diet is associated with lower prevalence of osteoarthritis: Data from the osteoarthritis initiative. Clin Nutr 36:1609-1614|
|Mitchell, Amanda M; Palettas, Marilly; Christian, Lisa M (2017) Fetal sex is associated with maternal stimulated cytokine production, but not serum cytokine levels, in human pregnancy. Brain Behav Immun 60:32-37|
|Orchard, Tonya S; Andridge, Rebecca R; Yee, Lisa D et al. (2017) Diet Quality, Inflammation, and Quality of Life in Breast Cancer Survivors: A Cross-Sectional Analysis of Pilot Study Data. J Acad Nutr Diet :|
|Shen, Qiwen; Yasmeen, Rumana; Marbourg, Jessica et al. (2017) Induction of innervation by encapsulated adipocytes with engineered vitamin A metabolism. Transl Res :|
|Walline, Jeffrey J; Gaume Giannoni, Amber; Sinnott, Loraine T et al. (2017) A Randomized Trial of Soft Multifocal Contact Lenses for Myopia Control: Baseline Data and Methods. Optom Vis Sci 94:856-866|
|Assani, Kaivon; Shrestha, Chandra L; Robledo-Avila, Frank et al. (2017) Human Cystic Fibrosis Macrophages Have Defective Calcium-Dependent Protein Kinase C Activation of the NADPH Oxidase, an Effect Augmented by Burkholderia cenocepacia. J Immunol 198:1985-1994|
|Hassan, B B; Elshafae, S M; Supsavhad, W et al. (2017) Feline Mammary Cancer. Vet Pathol 54:32-43|
|Zhang, Myron; Silverberg, Jonathan I; Kaffenberger, Benjamin H (2017) Prescription patterns and costs of acne/rosacea medications in Medicare patients vary by prescriber specialty. J Am Acad Dermatol 77:448-455.e2|
|Mitchell, Amanda M; Porter, Kyle; Christian, Lisa M (2017) Examination of the Role of Obesity in the Association Between Childhood Trauma and Inflammation During Pregnancy. Health Psychol :|
|Gillespie, Shannon L; Christian, Lisa M; Alston, Angela D et al. (2017) Childhood stress and birth timing among African American women: Cortisol as biological mediator. Psychoneuroendocrinology 84:32-41|
Showing the most recent 10 out of 397 publications