This is an applicafion for a Clinical and Translafional Science Award (CTSA) at the Albert Einstein College of Medicine partnered with Montefiore Medical Center. The Einstein-Montefiore Institute for Clinical and Trans- lational Research (ICTR) serves as the home of our CTSA program created in 2007 as the formal research partnership between the two institufions. The ICTR has status as an academic entity with committed space and resources, to advance clinical and translafional research (CTR), with authority to sponsor a PhD in clinical invesfigation and other training and career development programs. The ICTR has transformed CTR within our institufions, and contributed to significant changes beyond our walls. The goals for the new CTSA are;1) To provide integrated resources and services to support and expedite planning, implementafion, and completion of CTR across the entire range of research;2) To enhance quality, safety, and efficiency of CTR for all diseases and condifions in our environment;3) To develop new innovafions that advance clinical and translational sciences;4) To facilitate the training and career development of a robust translafional research workforce. To accomplish these goals, we propose an integrafive approach with cross-cutting support for T1-T4 translafional sciences, interoperable biomedical informafics, therapeufics development, child health research, and patient- and population-centered outcomes research. We also propose to build on research core services that have evolved and expanded including: 1) Clinical Trials and Regulatory Support Office (CTRSO);2) Clinical Invesfigafion Services Cores (CISC);3) Biostafisfics, Epidemiology &Research Design (BERD);4) Biomarker and Analyfic Research Core (BARC);5) Biospecimen Repository (BioR); 6) Community Engagement Consultafion Core (CECC);7) Research Informafics Core (RIC);and 8) Project Accelerafion Resource (PAR). Our Research Training, Education and Career Development program will create an educational environment with a learner-centered approach;focus on the core competencies developed by the CTSA;provide a menu of options to serve learners at various stages of development across the spectrum of clinical and translafional research;and to implement novel mentoring approaches.
This CTSA applicafion proposes an Institufional Clinical and Translafional Science Award (U54) program that conforms to the mission of the Nafional Center for Advancing Translafional Sciences, as expressed in RFA- TR-12-006.
|Blackstock, Oni J; Cunningham, Chinazo O; Haughton, Lorlette J et al. (2016) Higher eHealth Literacy is Associated With HIV Risk Behaviors among HIV-Infected Women Who Use the Internet. J Assoc Nurses AIDS Care 27:102-8|
|Ismail, Khadija; Nussbaum, Lisa; Sebastiani, Paola et al. (2016) Compression of Morbidity Is Observed Across Cohorts with Exceptional Longevity. J Am Geriatr Soc 64:1583-91|
|Friedman, Benjamin W; Cabral, Lisa; Adewunmi, Victoria et al. (2016) Diphenhydramine as Adjuvant Therapy for Acute Migraine: An Emergency Department-Based Randomized Clinical Trial. Ann Emerg Med 67:32-39.e3|
|Herold, Betsy C; Chen, Beatrice A; Salata, Robert A et al. (2016) Impact of Sex on the Pharmacokinetics and Pharmacodynamics of 1% Tenofovir Gel. Clin Infect Dis 62:375-82|
|Carter, George M; Esmaeili, Aryan; Shah, Hardikkumar et al. (2016) Probiotics in Human Immunodeficiency Virus Infection: A Systematic Review and Evidence Synthesis of Benefits and Risks. Open Forum Infect Dis 3:ofw164|
|Maradiaga, Jeronimo A; Nahvi, Shadi; Cunningham, Chinazo O et al. (2016) ""I Kicked the Hard Way. I Got Incarcerated."" Withdrawal from Methadone During Incarceration and Subsequent Aversion to Medication Assisted Treatments. J Subst Abuse Treat 62:49-54|
|Andreae, Michael H; Atchabahian, Arthur; McCrillis, Aileen M et al. (2016) Regional versus general anaesthesia for improved cognitive function after procedures other than cardiac surgery or neurosurgery in adult and paediatric patients. Cochrane Database Syst Rev 2016:|
|Nakra, Natasha A; Madan, Rebecca Pellett; Buckley, Niall et al. (2016) Loss of Innate Host Defense Following Unprotected Vaginal Sex. J Infect Dis 213:840-7|
|Rizzo, John-Ross; Hudson, Todd E; Dai, Weiwei et al. (2016) Rapid number naming in chronic concussion: eye movements in the King-Devick test. Ann Clin Transl Neurol 3:801-811|
|Keller, Marla J; Mesquita, Pedro M; Marzinke, Mark A et al. (2016) A phase 1 randomized placebo-controlled safety and pharmacokinetic trial of a tenofovir disoproxil fumarate vaginal ring. AIDS 30:743-51|
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