ICAC's goal is to include further development of cockroach allergen immunotherapy and consideration of new allergen immunotherapies;for example to mouse allergens;the development and execution of clinical and mechanistic studies targeted to inner-city asthma phenotypes, and interventions designed to prevent the incidence of asthma or its progression. In addition, the URECA birth cohort study will be continued to the end of the grant, when the participants will range from 14 to 16 years of age, with the goal to provide information on the immunologic basis of late childhood and adolescence-onset asthma, as well as the remission of asthma during the same years.

Public Health Relevance

ICAC is a multi-study, multi-center initiative to study the causes of the urban asthma epidemic that afflicts millions of children and to develop treatments to improve control of asthma in this population and for children in general.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project with Complex Structure Cooperative Agreement (UM1)
Project #
1UM1AI114271-01
Application #
8788464
Study Section
Special Emphasis Panel (ZAI1-MM-I (M2))
Program Officer
Dong, Gang
Project Start
2014-08-05
Project End
2021-07-31
Budget Start
2014-08-05
Budget End
2015-07-31
Support Year
1
Fiscal Year
2014
Total Cost
$9,949,825
Indirect Cost
$693,441
Name
University of Wisconsin Madison
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715