Abstract

In 1995 -1996, the study mailed a questionnaire to 3.5 million AARP members, aged 50-71 years, who resided in one of six states (California, Florida, Pennsylvania, New Jersey, North Carolina, and Louisiana) or in two metropolitan areas (Atlanta, Georgia and Detroit, Michigan). The questionnaire included a dietary section as well as lifestyle questions. Over 560,000 people returned the questionnaire satisfactorily, making this the largest in-depth study of nutrition and health ever conducted. In 1996-1997, the study mailed participants another questionnaire asking asked more detailed questions about lifestyle and health behavior. In 2004-2006 a follow-up questionnaire was mailed to update the information on selected risk factors and obtain non-cancer outcomes. The participants have been followed through the State Cancer Registry database to identify incident cancers and Social Security Administration Death Master File and National Death Index to identify cause-specific mortality. To maintain contact with the participants, the study have sent an annual newsletter containing the latest research and news about the study.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Intramural Research (Z01)
Project #
1Z01CP010196-02
Application #
7733749
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
2008
Total Cost
$1,455,420
Indirect Cost

  Institution

Name
Division of Cancer Epidemiology and Genetics
Department
Type
DUNS #
City
State
Country
United States
Zip Code

  Publications

Liu, Rui; Young, Michael T; Chen, Jiu-Chiuan et al. (2016) Ambient Air Pollution Exposures and Risk of Parkinson Disease. Environ Health Perspect 124:1759-1765
Gao, Jianjun; Liu, Rui; Zhao, Edward et al. (2015) Head injury, potential interaction with genes, and risk for Parkinson's disease. Parkinsonism Relat Disord 21:292-6
Liu, Rui; Baird, Donna; Park, Yikyung et al. (2014) Female reproductive factors, menopausal hormone use, and Parkinson's disease. Mov Disord 29:889-96
Dong, Jing; Beard, John D; Umbach, David M et al. (2014) Dietary fat intake and risk for Parkinson's disease. Mov Disord 29:1623-30
Dong, Jing; Gao, Jianjun; Nalls, Michael et al. (2014) Susceptibility loci for pigmentation and melanoma in relation to Parkinson's disease. Neurobiol Aging 35:1512.e5-1512.e10
Liu, Rui; Guo, Xuguang; Park, Yikyung et al. (2013) Alcohol Consumption, Types of Alcohol, and Parkinson's Disease. PLoS One 8:e66452
Gao, Jianjun; Nalls, Michael A; Shi, Min et al. (2012) An exploratory analysis on gene-environment interactions for Parkinson disease. Neurobiol Aging 33:2528.e1-6
Hamza, Taye H; Chen, Honglei; Hill-Burns, Erin M et al. (2011) Genome-wide gene-environment study identifies glutamate receptor gene GRIN2A as a Parkinson's disease modifier gene via interaction with coffee. PLoS Genet 7:e1002237
Gao, Jianjun; Xu, Hong; Weinberg, Clarice et al. (2011) An exploratory study on the CHRNA3-CHRNA5-CHRNB4 cluster, smoking, and Parkinson's disease. Neurodegener Dis 8:296-9
Schonfeld, S J; Ron, E; Kitahara, C M et al. (2011) Hormonal and reproductive factors and risk of postmenopausal thyroid cancer in the NIH-AARP Diet and Health Study. Cancer Epidemiol 35:e85-90

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