1. We completed analysis of the main case-control study and published approximately 50 reports in peer-reviewed journals. 2. We demonstrated that the patterns of risk vary according to the subtype of lymphoma. 3. We showed that genetic risk factors for occurrance of NHL also predicted survival;We're continuing to explore other subtypes to compare the patterns of etiology and survival. 4. To conduct a GWAS and to study the genetic polymorphism with more power, we are pooling data within Interlymph. 5. We continued to collaborate with InterLymph and we reported on the pooled estimates for overweight, sunlight, hepatitis C virus, hair dyes, and reproductive history. 6. We combined environmental data from other sources with study data to continue to investigate environmental risks. This work is ongoing.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Investigator-Initiated Intramural Research Projects (ZIA)
Project #
1ZIACP010170-13
Application #
8763627
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
13
Fiscal Year
2013
Total Cost
$868,892
Indirect Cost
Name
Division of Cancer Epidemiology and Genetics
Department
Type
DUNS #
City
State
Country
Zip Code
Linet, Martha S; Brown, Linda M; Mbulaiteye, Sam M et al. (2016) International long-term trends and recent patterns in the incidence of leukemias and lymphomas among children and adolescents ages 0-19 years. Int J Cancer 138:1862-74
Vijai, Joseph; Wang, Zhaoming; Berndt, Sonja I et al. (2015) A genome-wide association study of marginal zone lymphoma shows association to the HLA region. Nat Commun 6:5751
DellaValle, Curt T; Purdue, Mark P; Ward, Mary H et al. (2015) Validity of expert assigned retrospective estimates of occupational polychlorinated biphenyl exposure. Ann Occup Hyg 59:609-15
Paltiel, Ora; Tikellis, Gabriella; Linet, Martha et al. (2015) Birthweight and Childhood Cancer: Preliminary Findings from the International Childhood Cancer Cohort Consortium (I4C). Paediatr Perinat Epidemiol 29:335-45
Nordsborg, Rikke Baastrup; Sloan, Chantel D; Shahid, Haseeb et al. (2015) Investigation of spatio-temporal cancer clusters using residential histories in a case-control study of non-Hodgkin lymphoma in the United States. Environ Health 14:48
Morton, Lindsay M; Sampson, Joshua N; Cerhan, James R et al. (2014) Rationale and Design of the International Lymphoma Epidemiology Consortium (InterLymph) Non-Hodgkin Lymphoma Subtypes Project. J Natl Cancer Inst Monogr 2014:1-14
Morton, Lindsay M; Slager, Susan L; Cerhan, James R et al. (2014) Etiologic heterogeneity among non-Hodgkin lymphoma subtypes: the InterLymph Non-Hodgkin Lymphoma Subtypes Project. J Natl Cancer Inst Monogr 2014:130-44
Khalil, Mohammad O; Morton, Lindsay M; Devesa, Susan S et al. (2014) Incidence of marginal zone lymphoma in the United States, 2001-2009 with a focus on primary anatomic site. Br J Haematol 165:67-77
Chihara, Dai; Ito, Hidemi; Matsuda, Tomohiro et al. (2014) Differences in incidence and trends of haematological malignancies in Japan and the United States. Br J Haematol 164:536-45
Aschebrook-Kilfoy, Briseis; Cocco, Pierluigi; La Vecchia, Carlo et al. (2014) Medical history, lifestyle, family history, and occupational risk factors for mycosis fungoides and Sézary syndrome: the InterLymph Non-Hodgkin Lymphoma Subtypes Project. J Natl Cancer Inst Monogr 2014:98-105

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