In the past year, we have developed software for phosphoproteomic site-assignment and for clustering of dynamic data (in preparation for publication). We have also developed and published software to aid in the design of peptide-directed and fusion protein-directed antibodies called NHLBI-AbDesigner ( A paper describing this tool and illustrating its use has been published (Pisitkun et al. NHLBI-AbDesigner: An online tool for design of peptide-directed antibodies. American Journal of Physiology: Cell Physiology. Epub in advance of printing, 2011). We have also developed software to produce sequence logos from phosphoproteomic data called Phosphologo (in review). A list of available software programs can be found at Finally, we have maintained an improved our proteomics and transcriptomic databases. A list of these databases can be found online at

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LeMaire, Sophia M; Raghuram, Viswanathan; Grady, Cameron R et al. (2017) Serine/threonine phosphatases and aquaporin-2 regulation in renal collecting duct. Am J Physiol Renal Physiol 312:F84-F95
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Hyndman, Kelly A; Knepper, Mark A (2017) Dynamic regulation of lysine acetylation: the balance between acetyltransferase and deacetylase activities. Am J Physiol Renal Physiol 313:F842-F846
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Zhao, Yue; Yang, Chin-Rang; Raghuram, Viswanathan et al. (2016) BIG: A large-scale data integration tool for renal physiology. Am J Physiol Renal Physiol :ajprenal.00249.2016
Cheng, Lei; Pisitkun, Trairak; Knepper, Mark A et al. (2016) Peptide Labeling Using Isobaric Tagging Reagents for Quantitative Phosphoproteomics. Methods Mol Biol 1355:53-70
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