We have developed software for phosphoproteomic site-assignment and for clustering of dynamic data. We have also developed and published software to aid in the design of peptide-directed and fusion protein-directed antibodies called NHLBI-AbDesigner (http://helixweb.nih.gov/AbDesigner/). A paper describing this tool and illustrating its use has been published (Pisitkun et al. NHLBI-AbDesigner: An online tool for design of peptide-directed antibodies. American Journal of Physiology: Cell Physiology. Epub in advance of printing, 2011). We have also developed software to produce sequence logos from phosphoproteomic data called Phosphologo. A list of available software programs can be found at http://helixweb.nih.gov/ESBL/. Finally, we have maintained an improved our proteomics and transcriptomic databases. A list of these databases can be found online at http://helixweb.nih.gov/ESBL/Database/index.html.

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National Heart, Lung, and Blood Institute
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Sanghi, Akshay; Zaringhalam, Matthew; Corcoran, Callan C et al. (2014) A knowledge base of vasopressin actions in the kidney. Am J Physiol Renal Physiol 307:F747-55
Xie, Luke; Subashi, Ergys; Qi, Yi et al. (2014) Four-dimensional MRI of renal function in the developing mouse. NMR Biomed 27:1094-102
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Yu, Panpan; Pisitkun, Trairak; Wang, Guanghui et al. (2013) Global analysis of neuronal phosphoproteome regulation by chondroitin sulfate proteoglycans. PLoS One 8:e59285