The research team is actively recruiting participants for their studies that investigate the molecular-genetic correlates, as well as possible therapeutics of cancer-related fatigue. Recruitment was conducted by self-referral, referrals from other National Cancer Institute providers, and/or from the Patient Recruitment and Public Liaison Office. The PI is working closely with collaborators from the Multidisciplinary Prostate Cancer Clinics of the National Cancer Institute to improve recruitment of interested individuals. There is an increased inquiry from both patients and investigators from NCI about the protocol.

Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
2013
Total Cost
$167,844
Indirect Cost
Name
National Institute of Nursing Research
Department
Type
DUNS #
City
State
Country
Zip Code
Saligan, L N; Lukkahatai, N; Holder, G et al. (2016) Lower brain-derived neurotrophic factor levels associated with worsening fatigue in prostate cancer patients during repeated stress from radiation therapy. World J Biol Psychiatry 17:608-614
Feng, Li Rebekah; Wolff, Brian S; Lukkahatai, Nada et al. (2016) Exploratory Investigation of Early Biomarkers for Chronic Fatigue in Prostate Cancer Patients Following Radiation Therapy. Cancer Nurs :
Filler, Kristin; Saligan, Leorey N (2016) Defining cancer-related fatigue for biomarker discovery. Support Care Cancer 24:5-7
Feng, Li Rebekah; Dickinson, Kristin; Kline, Neila et al. (2016) Different Phenotyping Approaches Lead to Dissimilar Biologic Profiles in Men With Chronic Fatigue After Radiation Therapy. J Pain Symptom Manage 52:832-840
Saligan, Leorey N; Olson, Karin; Filler, Kristin et al. (2015) The biology of cancer-related fatigue: a review of the literature. Support Care Cancer 23:2461-78
Filler, Kristin; Lyon, Debra; Bennett, James et al. (2014) Association of Mitochondrial Dysfunction and Fatigue: A Review of the Literature. BBA Clin 1:12-23
Saligan, Leorey N; Fernández-Martínez, Juan Luis; deAndrés-Galiana, Enrique J et al. (2014) Supervised classification by filter methods and recursive feature elimination predicts risk of radiotherapy-related fatigue in patients with prostate cancer. Cancer Inform 13:141-52
Lukkahatai, Nada; Saligan, Leorey N (2013) Association of catastrophizing and fatigue: a systematic review. J Psychosom Res 74:100-9
Saligan, L N; Kim, H S (2012) A systematic review of the association between immunogenomic markers and cancer-related fatigue. Brain Behav Immun 26:830-48