The IPDC was one of three components of the molecular imaging aspect of the NIH Roadmap initiative, with the other two being high specificity/high sensitivity probes, and the set-up of an imaging probe database (MICAD). The IPDC produces known and new imaging probes for the NIH research community. The new IPDC laboratories began full operations early in calendar year 2007. The IPDC is now part of the NIH Intramural Program. For a complete listing of our projects, please refer to our website: https://intramural.nhlbi.nih.gov/OFFICES/IPDC/Pages/IPDCProjectList.aspx

Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
2011
Total Cost
$2,998,254
Indirect Cost
Name
National Heart, Lung, and Blood Institute
Department
Type
DUNS #
City
State
Country
Zip Code
Basuli, Falguni; Zhang, Xiang; Woodroofe, Carolyn C et al. (2017) Fast indirect fluorine-18 labeling of protein/peptide using the useful 6-fluoronicotinic acid-2,3,5,6-tetrafluorophenyl prosthetic group: A method comparable to direct fluorination. J Labelled Comp Radiopharm 60:168-175
Zhang, Xiang; Basuli, Falguni; Shi, Zhen-Dan et al. (2016) Automated synthesis of [(18)F](2S,4R)-4-fluoroglutamine on a GE TRACERlab™ FX-N Pro module. Appl Radiat Isot 112:110-4
Strickland, Madeleine; Schwieters, Charles D; Göbl, Christoph et al. (2016) Characterizing the magnetic susceptibility tensor of lanthanide-containing polymethylated-DOTA complexes. J Biomol NMR 66:125-139
Basuli, Falguni; Zhang, Xiang; Jagoda, Elaine M et al. (2016) Facile room temperature synthesis of fluorine-18 labeled fluoronicotinic acid-2,3,5,6-tetrafluorophenyl ester without azeotropic drying of fluorine-18. Nucl Med Biol 43:770-772
Sato, Kazuhide; Gorka, Alexander P; Nagaya, Tadanobu et al. (2016) Effect of charge localization on the in vivo optical imaging properties of near-infrared cyanine dye/monoclonal antibody conjugates. Mol Biosyst 12:3046-56
Opina, Ana Christina L; Strickland, Madeleine; Lee, Yong-Sok et al. (2016) Analysis of the isomer ratios of polymethylated-DOTA complexes and the implications on protein structural studies. Dalton Trans 45:4673-87
Sato, Kazuhide; Gorka, Alexander P; Nagaya, Tadanobu et al. (2016) Role of Fluorophore Charge on the In Vivo Optical Imaging Properties of Near-Infrared Cyanine Dye/Monoclonal Antibody Conjugates. Bioconjug Chem 27:404-13
Rosales, Tilman; Sackett, Dan L; Xu, Jianhua et al. (2015) STAQ: A route toward low power, multicolor nanoscopy. Microsc Res Tech 78:343-55
Basuli, Falguni; Li, Changhui; Xu, Biying et al. (2015) Synthesis of fluorine-18 radio-labeled serum albumins for PET blood pool imaging. Nucl Med Biol 42:219-25
Opina, Ana Christina; Wong, Karen J; Griffiths, Gary L et al. (2015) Preparation and long-term biodistribution studies of a PAMAM dendrimer G5-Gd-BnDOTA conjugate for lymphatic imaging. Nanomedicine (Lond) 10:1423-37

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