The Hematopathology Fellowship has been highly successful in attracting outstanding applicants and in providing them with training in hematopathology, emphasizing outstanding clinical diagnosis, and specialized diagnostic tools including molecular diagnostics and flow cytometry. The fellowship has been ACGME accredited since 2000, and graduating fellows have had a nearly a 100% first time pass rate on the accrediting examination given by the American Board of Pathology. Graduating fellows have gone on to establish independent careers in academic medicine, including appointments in recent years at the Moffit Cancer Center, Loyola University, The Methodist Hospital (Weill Cornell Medical School), The University of California -Davis, The Mayo Clinic, Memorial Sloan Kettering Cancer Center, and the Cleveland Clinic. Two of recent graduates have successfully competed for independent NIH funding. Fellows are encouraged to participate in clinical research, and have successfully completed studies on a variety of topics, as briefly mentioned below. Eberle, F. C., J. Y. Song, L. Xi, M. Raffeld, N. L. Harris, W. H. Wilson, S. Pittaluga and E. S. Jaffe (2012). """"""""Nodal Involvement by Cutaneous CD30-positive T-cell Lymphoma Mimicking Classical Hodgkin Lymphoma."""""""" Am J Surg Pathol 36(5): 716-25.Huppmann, A., M. Roullet, M. Raffeld and E. Jaffe (in press ). """"""""Angioimmunoblastic T-cell lymphoma partially obscured by an EBV-negative clonal plasma cell proliferation."""""""" Journal of Clinical Oncology.Jegalian, A. G., F. C. Eberle, S. D. Pack, M. Mirvis, M. Raffeld, S. Pittaluga and E. S. Jaffe (2011). """"""""Follicular lymphoma in situ: clinical implications and comparisons with partial involvement by follicular lymphoma."""""""" Blood 118(11): 2976-84.Menon, M. P., A. Jegalion, M. Raffeld, S. Pittaluga, L. Xi and E. S. Jaffe (2012). """"""""Primary CNS T-Cell Lymphomas: Clinical, Morphologic, Immunophenotypic and Molecular Analysis."""""""" Modern Pathology 25: 355A-355A.Song, J. Y., T. Strom, M. Raffeld, S. Pittaluga and E. S. Jaffe (2011). """"""""Peripheral T-Cell Lymphoma With Aberrant Expression of CD30, CD15, and CD20."""""""" J Clin Oncol.Summers, T. A., F. C. Eberle, S. Pittaluga, W. H. Wilson, K. Dunleavy, M. Raffeld, S. M. Hewitt and E. S. Jaffe (2011). """"""""Gray zone lymphomas: becoming more black and white."""""""" Mod Pathol 24, Suppl 1.: 324A.Summers, T. A. and E. S. Jaffe (2011). """"""""Hairy cell leukemia diagnostic criteria and differential diagnosis."""""""" Leuk Lymphoma.Venkataraman, G., K. A. Rizzo, J. J. Chavez, B. Streubel, M. Raffeld, E. S. Jaffe and S. Pittaluga (2011). """"""""Marginal zone lymphomas involving meningeal dura: possible link to IgG4-related diseases."""""""" Mod Pathol 24(3): 355-66.Venkataraman, G., A. Traverse-Glehen, J. Y. Song, F. C. Eberle, J. C. Hanson, S. Dirnhofer, A. Tzankov, G. Heinze, M. A. Raffeld, S. Pittaluga and E. S. Jaffe (2011). """"""""Aberrant T-Cell Antigen Expression in Classical Hodgkin Lymphoma Is Associated with Decreased Event-Free Survival (EFS) and Overall Survival (OS)."""""""" Laboratory Investigation 91: 326A-327A.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Clinical Training Intramural Research (ZIE)
Project #
1ZIEBC011241-04
Application #
8554195
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
2012
Total Cost
$569,946
Indirect Cost
Name
National Cancer Institute Division of Basic Sciences
Department
Type
DUNS #
City
State
Country
Zip Code
Ganapathi, Karthik A; Jobanputra, Vaidehi; Iwamoto, Fabio et al. (2016) The genetic landscape of dural marginal zone lymphomas. Oncotarget :
Wang, Hao-Wei; Pittaluga, Stefania; Jaffe, Elaine S (2016) Multicentric Castleman disease: Where are we now? Semin Diagn Pathol 33:294-306
Xiao, Wenbin; Chen, Wayne W; Sorbara, Lynn et al. (2016) Hodgkin lymphoma variant of Richter transformation: morphology, Epstein-Barr virus status, clonality, and survival analysis-with comparison to Hodgkin-like lesion. Hum Pathol 55:108-16
Menon, Madhu P; Nicolae, Alina; Meeker, Hillary et al. (2015) Primary CNS T-cell Lymphomas: A Clinical, Morphologic, Immunophenotypic, and Molecular Analysis. Am J Surg Pathol 39:1719-29
Gong, Shunyou; Auer, Iwona; Duggal, Rajan et al. (2015) Epstein-Barr virus-associated inflammatory pseudotumor presenting as a colonic mass. Hum Pathol 46:1956-61
Xie, Yi; Pittaluga, Stefania; Jaffe, Elaine S (2015) The histological classification of diffuse large B-cell lymphomas. Semin Hematol 52:57-66
Song, Joo Y; Pittaluga, Stefania; Dunleavy, Kieron et al. (2015) Lymphomatoid granulomatosis--a single institute experience: pathologic findings and clinical correlations. Am J Surg Pathol 39:141-56
Lee, Yi-Shan; Filie, Armando; Arthur, Diane et al. (2015) Breast implant-associated anaplastic large cell lymphoma in a patient with Li-Fraumeni syndrome. Histopathology 67:925-7
Menon, Madhu P; Evbuomwan, Moses O; Rosai, Juan et al. (2014) A subset of Rosai-Dorfman disease cases show increased IgG4-positive plasma cells: another red herring or a true association with IgG4-related disease? Histopathology 64:455-9
Huppmann, Alison R; Nicolae, Alina; Slack, Graham W et al. (2014) EBV may be expressed in the LP cells of nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) in both children and adults. Am J Surg Pathol 38:316-24

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