The speciality field of laboratory animal medicine and care covers a diverse array of responsibilities. The Rocky Mountain Veterinary Branch (RMVB) staff may encounter unusual clinical cases and emerging murine infectious diseases during their normal work duties that are conducive to study. The construction and management of facilities for human emerging diseases and potential bioterrorism agent research also results in unique experiences. Investigation of these observations and experiences contributes to advancing the body of knowledge within the laboratory animal field. The diligent RMVB staff provide the support necessary for DIR investigators to conduct cutting edge research.

Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
2013
Total Cost
$5,497,146
Indirect Cost
City
State
Country
Zip Code
Marzi, Andrea; Murphy, Aisling A; Feldmann, Friederike et al. (2016) Cytomegalovirus-based vaccine expressing Ebola virus glycoprotein protects nonhuman primates from Ebola virus infection. Sci Rep 6:21674
Malachowa, Natalia; Kobayashi, Scott D; Porter, Adeline R et al. (2016) Contribution of Staphylococcus aureus Coagulases and Clumping Factor A to Abscess Formation in a Rabbit Model of Skin and Soft Tissue Infection. PLoS One 11:e0158293
Short, Kirsty R; Kasper, Jennifer; van der Aa, Stijn et al. (2016) Influenza virus damages the alveolar barrier by disrupting epithelial cell tight junctions. Eur Respir J 47:954-66
Munster, Vincent J; Adney, Danielle R; van Doremalen, Neeltje et al. (2016) Replication and shedding of MERS-CoV in Jamaican fruit bats (Artibeus jamaicensis). Sci Rep 6:21878
Marzi, Andrea; Hanley, Patrick W; Haddock, Elaine et al. (2016) Efficacy of Vesicular Stomatitis Virus-Ebola Virus Postexposure Treatment in Rhesus Macaques Infected With Ebola Virus Makona. J Infect Dis :
Baseler, Laura J; Falzarano, Darryl; Scott, Dana P et al. (2016) An Acute Immune Response to Middle East Respiratory Syndrome Coronavirus Replication Contributes to Viral Pathogenicity. Am J Pathol 186:630-8
Hanley, Patrick W; Barnhart, Kirstin F; Abee, Christian R et al. (2015) Methicillin-Resistant Staphylococcus aureus Prevalence among Captive Chimpanzees, Texas, USA, 2012(1). Emerg Infect Dis 21:2158-60
Marzi, Andrea; Feldmann, Friederike; Hanley, Patrick W et al. (2015) Delayed Disease Progression in Cynomolgus Macaques Infected with Ebola Virus Makona Strain. Emerg Infect Dis 21:1777-83
Hoenen, Thomas; Marzi, Andrea; Scott, Dana P et al. (2015) Soluble Glycoprotein Is Not Required for Ebola Virus Virulence in Guinea Pigs. J Infect Dis :
Marzi, Andrea; Robertson, Shelly J; Haddock, Elaine et al. (2015) EBOLA VACCINE. VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain. Science 349:739-42

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