This award from the Chemistry Research Instrumentation Program will assist the Department of Chemistry at the University of Pennsylvania in the purchase of an x-ray diffractometer and associated data collection and analysis system and an upgrade of an older x-ray diffractometer. This new instrument will enhance greatly research in a number of areas including the following: 1) Transition metal complexes of organosilicon compounds: New structures and catalysts, 2) Catalytic dehydrogenative coupling of alkylsilanes to carbosilanes, 3) Natural product structure determination, synthesis and organic photochemistry: Hitachimycin (a.k.a. Stubomycin), a novel antitumor agent, 4) Bioorganic chemistry: Non-peptidal peptidomimetics, 5) Materials chemistry and inorganic catalysis: New polymeric precursors to boron-based ceramics, 6) Ferroelectric metal-oxo polymers and metal-insulator transitions in metal-oxo polymers, 7) Organometallic reactivity of metallomacrocyclic complexes, 8) Strategies for synthesis of anti-tumor compounds. %%% The x-ray diffractometer is used to make accurate and precise measurements of the full three-dimensional structure of a molecule. The information obtained gives the precise values of all the bond distances and bond angles of a given molecule and it gives accurate information about the spatial arrangement of that molecule relative to the neighboring molecules.

Agency
National Science Foundation (NSF)
Institute
Division of Chemistry (CHE)
Type
Standard Grant (Standard)
Application #
9305794
Program Officer
Thomas C. Farrar
Project Start
Project End
Budget Start
1993-07-01
Budget End
1994-12-31
Support Year
Fiscal Year
1993
Total Cost
$203,600
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19104