This Small Business Technology Transfer Research (STTR) Phase I project proposes to use high pressures for disaggregation and proper refolding of aggregated proteins in commercial IVIg (immunoglobins for intravenous administration) formulations.

The commercial application of this project will be in improved quality of therapeutic proteins for intravenous administration. Increased process yields will lower patient costs for IVIg therapies, and IVIg formulations with dramatically diminished aggregate content will lower side effects and reduce the risk of severe complications.

Agency
National Science Foundation (NSF)
Institute
Division of Industrial Innovation and Partnerships (IIP)
Type
Standard Grant (Standard)
Application #
0420061
Program Officer
George B. Vermont
Project Start
Project End
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
Fiscal Year
2004
Total Cost
$98,181
Indirect Cost
Name
Barofold, Inc.
Department
Type
DUNS #
City
Boulder
State
CO
Country
United States
Zip Code
80304