This training grant will utilize an existing research infrastructure in Peru to train Peruvian scientists and health professionals in infectious disease research. This proposal expands on the foundation of a successful, longstanding, NIH-funded training and research collaboration between the Universidad Peruana Cayetano Heredia (UPCH) in Lima, Peru and the Johns Hopkins School of Public Health (JHSPH). Over the past 20 years, this program has trained over 67 Peruvians and 223 graduate and post-graduate students of other nationalities. In Peru, a mentorship program will be used to train students in research methodology.
The specific aims of this program are (1) to train two Peruvian students at the Masters level at UPCH in Public Health and/or Biochemistry; (2) to set up one three-day research seminar to train individuals from outside Lima in cestode and molecular biology research methodology, as well as bioethics, responsible research, and grant writing skills; (3) to enable fifteen Peruvian students to attend the Tropical Medicine and Public Health Summer Institute at JHSPH over a five year period; and (4) to train two Peruvian PhD candidates at JHSPH in International Health over a five year period (5). Training will occur within a broad-based infectious disease research program, with primary emphasis on Chagas? disease, cysticercosis, and tuberculosis. Other specific diseases to be targeted include Parasitic Diseases in general (diphyllobothriasis, strongiloidiasis, coenurosis), infections of the nervous system, and diarrheal disease. The program also has a long history of successful and innovative investigation in enteric parasitic infections, Helicobacter pylori infection, and more recently, leptospirosis and malaria. Studies in all of these areas are ongoing and provide a wide breadth of training opportunities. The organization of our program is not dependent on any single individual or institution. Rather, it has achieved sustainability because of a wide network of collaborators that include multiple American and foreign universities. Mentorship will be provided by local scientists as well as by visiting faculty from overseas institutions. ? ? ? ? ?

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
5D43TW001140-07
Application #
7264643
Study Section
Special Emphasis Panel (ZRG1-ICP2-B (50))
Program Officer
Sina, Barbara J
Project Start
1999-07-01
Project End
2011-03-31
Budget Start
2007-04-01
Budget End
2008-03-31
Support Year
7
Fiscal Year
2007
Total Cost
$131,914
Indirect Cost
Name
Universidad Peruana Cayetano Heredia
Department
Type
DUNS #
934798430
City
Lima
State
Country
Peru
Zip Code
LIMA -31
Proaño, Alvaro; Bui, David P; López, José W et al. (2018) Cough Frequency During Treatment Associated With Baseline Cavitary Volume and Proximity to the Airway in Pulmonary TB. Chest 153:1358-1367
Gomez-Puerta, Luis A; Garcia, Hector H; Gonzalez, Armando E et al. (2018) Experimental porcine cysticercosis using infected beetles with Taenia solium eggs. Acta Trop 183:92-94
Duque, Kevin R; Escalaya, Alejandro L; Zapata, Willy et al. (2018) Clinical topography relationship in patients with parenchymal neurocysticercosis and seizures. Epilepsy Res 145:145-152
Mejia Maza, Alan; Carmen-Orozco, Rogger P; Carter, Emma S et al. (2018) Axonal swellings and spheroids: a new insight into the pathology of neurocysticercosis. Brain Pathol :
Arroyo, Gianfranco; Rodriguez, Silvia; Lescano, Andres G et al. (2018) Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients With Neurocysticercosis. Clin Infect Dis 66:282-288
Garvey, Brian T; Moyano, Luz M; Ayvar, Viterbo et al. (2018) Neurocysticercosis among People Living Near Pigs Heavily Infected with Cysticercosis in Rural Endemic Peru. Am J Trop Med Hyg 98:558-564
Garcia, Hector H; Castillo, Yesenia; Gonzales, Isidro et al. (2018) Low sensitivity and frequent cross-reactions in commercially available antibody detection ELISA assays for Taenia solium cysticercosis. Trop Med Int Health 23:101-105
Nash, Theodore E; Bustos, Javier A; Garcia, Hector H et al. (2017) Disease Centered Around Calcified Taenia solium Granuloma. Trends Parasitol 33:65-73
Carrasco-Escobar, Gabriel; Gamboa, Dionicia; Castro, Marcia C et al. (2017) Micro-epidemiology and spatial heterogeneity of P. vivax parasitaemia in riverine communities of the Peruvian Amazon: A multilevel analysis. Sci Rep 7:8082
Pajuelo, Mónica J; Eguiluz, María; Roncal, Elisa et al. (2017) Genetic variability of Taenia solium cysticerci recovered from experimentally infected pigs and from naturally infected pigs using microsatellite markers. PLoS Negl Trop Dis 11:e0006087

Showing the most recent 10 out of 78 publications