Malaria is a major public health problem in Africa. Despite the importance of mosquito vectors in malaria transmission, the overall capacity for research in medical entomology in African countries is particularly weak. The goal of this training grant is to enhance the research capacity on malaria vectors in Kenya and other African countries by advancing the career development of promising young scientists from malaria-endemic African countries and by transferring new technologies to African scientists. The training will be focused on 3 critical areas of mosquito population biology: population regulation of African malaria vectors, larval control using biological insecticides, and population biology of transgenic mosquitoes. The training will be conducted primarily in Kenya and will involve long-term training of Ph.D. students, postdoctoral fellows and short-term training of junior university faculty and research scientists from sub-Saharan countries. A series of short training courses will be given in Kenya to enhance the skills of the trainees in data management, biostatistics and geographic information technology. The training program will also support trainees to come to the US for research-oriented training. The research training program will fill 2 major gaps in medical entomology research in Africa by: 1) strengthening research on vector ecology and genetics, and 2) promoting the integration of geographic information technology and molecular biology techniques with field-based malaria vector research. This training program will contribute significantly to the career development of African scientists by equipping them with new technologies, by providing opportunities for them to develop valuable Africa-wide and international linkages, and by enabling them to develop independent or collaborative research projects.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
5D43TW001505-07
Application #
7125994
Study Section
Special Emphasis Panel (ZRG1-ICP-2 (91))
Program Officer
Sina, Barbara J
Project Start
2000-09-29
Project End
2010-03-31
Budget Start
2006-04-01
Budget End
2007-03-31
Support Year
7
Fiscal Year
2006
Total Cost
$142,158
Indirect Cost
Name
University of California Irvine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
046705849
City
Irvine
State
CA
Country
United States
Zip Code
92697
Taffese, Hiwot S; Hemming-Schroeder, Elizabeth; Koepfli, Cristian et al. (2018) Malaria epidemiology and interventions in Ethiopia from 2001 to 2016. Infect Dis Poverty 7:103
Kapesa, Anthony; Kweka, Eliningaya J; Atieli, Harrysone et al. (2018) The current malaria morbidity and mortality in different transmission settings in Western Kenya. PLoS One 13:e0202031
Kahindi, Samuel C; Muriu, Simon; Derua, Yahya A et al. (2018) Efficacy and persistence of long-lasting microbial larvicides against malaria vectors in western Kenya highlands. Parasit Vectors 11:438
Koepfli, Cristian; Yan, Guiyun (2018) Plasmodium Gametocytes in Field Studies: Do We Measure Commitment to Transmission or Detectability? Trends Parasitol 34:378-387
Derua, Yahya A; Kahindi, Samuel C; Mosha, Franklin W et al. (2018) Microbial larvicides for mosquito control: Impact of long lasting formulations of Bacillus thuringiensis var. israelensis and Bacillus sphaericus on non-target organisms in western Kenya highlands. Ecol Evol 8:7563-7573
Kapesa, Anthony; Kweka, Eliningaya J; Zhou, Guofa et al. (2018) Utility of passive malaria surveillance in hospitals as a surrogate to community infection transmission dynamics in western Kenya. Arch Public Health 76:39
Aidoo, Ebenezer K; Afrane, Yaw A; Machani, Maxwell Gesuge et al. (2018) Reactive case detection of Plasmodium falciparum in western Kenya highlands: effective in identifying additional cases, yet limited effect on transmission. Malar J 17:111
Hemming-Schroeder, Elizabeth; Umukoro, Emuejevuoke; Lo, Eugenia et al. (2018) Impacts of Antimalarial Drugs on Plasmodium falciparum Drug Resistance Markers, Western Kenya, 2003-2015. Am J Trop Med Hyg 98:692-699
Zemene, Endalew; Koepfli, Cristian; Tiruneh, Abebaw et al. (2018) Detection of foci of residual malaria transmission through reactive case detection in Ethiopia. Malar J 17:390
Zhong, Daibin; Lo, Eugenia; Wang, Xiaoming et al. (2018) Multiplicity and molecular epidemiology of Plasmodium vivax and Plasmodium falciparum infections in East Africa. Malar J 17:185

Showing the most recent 10 out of 103 publications