Molecular Analysis of Second Site Reversion to Virulence

Schoepp, Randal J.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Postdoctoral Individual National Research Service Award (F32)
• Project #: 5F32AI008317-03
• Application #: 2058528
• Study Section: Immunology, Virology, and Pathology Study Section (IVP)
• Project Start: 1992-10-01
• Budget Start: 1992-10-01
• Budget End: 1993-09-30
• Support Year: 3
• Fiscal Year: 1992

Institution

• Name: University of North Carolina Chapel Hill
• Department: Microbiology/Immun/Virology
• Type: Schools of Medicine
• DUNS #: 078861598
• City: Chapel Hill
• State: NC
• Country: United States
• Zip Code: 27599

Publications

Schoepp, R J; Johnston, R E (1993) Directed mutagenesis of a Sindbis virus pathogenesis site. Virology 193:149-59

Schoepp, R J; Johnston, R E (1993) Sindbis virus pathogenesis: phenotypic reversion of an attenuated strain to virulence by second-site intragenic suppressor mutations. J Gen Virol 74 ( Pt 8):1691-5

Meyer, W J; Gidwitz, S; Ayers, V K et al. (1992) Conformational alteration of Sindbis virion glycoproteins induced by heat, reducing agents, or low pH. J Virol 66:3504-13