This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.This project focuses upon Infrastructure development in Computational Biology and Bioinformatics as part of the Core Resources at the Center for Biomedical Research (CBR) at Tuskegee University. Research involving advanced information technologies, the Internet and databases is crucial in examining and analyzing patterns of disease occurrence, genetic traits and molecular level dynamics. The key strategy in our endeavors in the core Bioinformatics is to upgrade the infrastructure and expertise of our scientists in computational biology and bioinformatics, acquire advanced computational and network resources and promote active research that exploits these technologies in health disparity studies. Server Development: Currently we have four servers: Three Red Hat Enterprise Linux ES and one Microsoft 2003 server. The software on the servers is accessible to computers on the campus. Website development: We have developed the following websites: a) TU's RCMI website: b)The College of Veterinary Medicine, Nursing and Allied Health (CVMNAH) website c) The health disparities website Which has a rich resources of health disparity database for the 12 black belt counties of AL.d) The data warehouse website This also has an online application for admission into the CVMNAH.e) The Bioinformatics website, under the TU's RCMI website, has a rich variety of selected resources in different categories and data which can be used by scientists interested in the area of bioinformatics and health disparities The Annual Biomedical Research Symposium: As part of the strategy to promote sharing of biomedical research activities that are in progress as well as to address national issues dealing with Health Disparities, CCEBRA organized nine annual biomedical research symposiums which were held during the last week of every September at the Kellogg Conference Center, Tuskegee University. Shared Resource: CCEBRA has been providing service in statistical analysis for faculty and researchers at TU. NCBI field guide in Tuskegee University: CCEBRA at TU hosted two courses entitled 'A Field Guide to GenBank and NCBI Molecular Biology Resources'. The National Center for Biotechnology Information (NCBI), a division of the National Library of Medicine and the courses were given by instructors from NCBI. See the sample at:

National Institute of Health (NIH)
National Center for Research Resources (NCRR)
Research Centers in Minority Institutions Award (G12)
Project #
Application #
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Tuskegee University
Other Domestic Higher Education
United States
Zip Code
Mukherjee, Angana; Hollern, Daniel P; Williams, Oluwasina G et al. (2018) A Review of FOXI3 Regulation of Development and Possible Roles in Cancer Progression and Metastasis. Front Cell Dev Biol 6:69
Yates, Clayton; Long, Mark D; Campbell, Moray J et al. (2017) miRNAs as drivers of TMPRSS2-ERG negative prostate tumors in African American men. Front Biosci (Landmark Ed) 22:212-229
Chowdhury, Rupak; David, Nganwa; Bogale, Asseged et al. (2016) Assessing the Key Attributes of Low Utilization of Mammography Screening and Breast-self Exam among African-American Women. J Cancer 7:532-7
Jones, Jacqueline; Mukherjee, Angana; Karanam, Balasubramanyam et al. (2016) African Americans with pancreatic ductal adenocarcinoma exhibit gender differences in Kaiso expression. Cancer Lett 380:513-22
Wang, Honghe; Liu, Wei; Black, ShaNekkia et al. (2016) Kaiso, a transcriptional repressor, promotes cell migration and invasion of prostate cancer cells through regulation of miR-31 expression. Oncotarget 7:5677-89
Reams, R Renee; Jones-Triche, Jacqueline; Chan, Owen T M et al. (2015) Immunohistological analysis of ABCD3 expression in Caucasian and African American prostate tumors. Biomed Res Int 2015:132981
Arora, Ritu; Schmitt, David; Karanam, Balasubramanyam et al. (2015) Inhibition of the Warburg effect with a natural compound reveals a novel measurement for determining the metastatic potential of breast cancers. Oncotarget 6:662-78
Jones, Jacqueline; Wang, Honghe; Karanam, Balasubramanyam et al. (2014) Nuclear localization of Kaiso promotes the poorly differentiated phenotype and EMT in infiltrating ductal carcinomas. Clin Exp Metastasis 31:497-510
Okumu, Lilian A; Braden, Tim D; Vail, Krystal et al. (2014) Low androgen induced penile maldevelopment involves altered gene expression of biomarkers of smooth muscle differentiation and a key enzyme regulating cavernous smooth muscle cell tone. J Urol 192:267-73
Theodore, Shaniece C; Davis, Melissa; Zhao, Fu et al. (2014) MicroRNA profiling of novel African American and Caucasian Prostate Cancer cell lines reveals a reciprocal regulatory relationship of miR-152 and DNA methyltranferase 1. Oncotarget 5:3512-25

Showing the most recent 10 out of 101 publications