Description and Key Personnel: Description The objective of the Wilmer Clinician-Scientist Training Program (CSTP) is to foster the development of clinician-scientists through mentored training by our experienced research faculty. The Wilmer Institute has a well-developed program for clinician-scientist training that utilizes governmental grants, private philanthropy, faculty commitment to education, and core facilities throughout the Johns Hopkins School of Medicine and the Bloomberg School of Public Health. The Wilmer CSTP program uniquely merges clinical investigation into visual disorders with the methodologies of clinical trials, public health, epidemiology, outcomes assessment and the finest in laboratory investigation in molecular biology, molecular genetics, and gene therapy. To continue our successful program in the career development of clinician-scientists, we seek a continuation of a total of 3 positions under the K12 mechanism, enrolling each of the 3 candidates for training periods of up to 4 years. Key Personnel Principal Investigator: Harry A. Quigley, MD, Administrator: Patricia Tracey, and the members of the CSTP advisory committee. Sheila West, Don Zack, Peter Campochiaro, Oliver Schein, James Handa, Shannath Merbs, Jennifer Thorne, and Gerry Lutty

Public Health Relevance

Our specific objective is to provide the training and mentorship that will lead each of these young persons to be successful as faculty members in Schools of Medicine and Public Health and to achieve funded, independent research programs.

National Institute of Health (NIH)
National Eye Institute (NEI)
Physician Scientist Award (Program) (PSA) (K12)
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Special Emphasis Panel (ZEY1-VSN (10))
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Agarwal, Neeraj
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Johns Hopkins University
Schools of Medicine
United States
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Eghrari, Allen O; Vasanth, Shivakumar; Gapsis, Briana C et al. (2018) Identification of a Novel TCF4 Isoform in the Human Corneal Endothelium. Cornea 37:899-903
Hessen, Michelle M; Vahedi, Sina; Khoo, Chloe T et al. (2018) Clinical and genetic investigation of amantadine-associated corneal edema. Clin Ophthalmol 12:1367-1371
Eghrari, Allen O; Mumtaz, Aisha A; Garrett, Brian et al. (2017) Automated Retroillumination Photography Analysis for Objective Assessment of Fuchs Corneal Dystrophy. Cornea 36:44-47
Eghrari, Allen O; Vasanth, Shivakumar; Wang, Jiangxia et al. (2017) CTG18.1 Expansion in TCF4 Increases Likelihood of Transplantation in Fuchs Corneal Dystrophy. Cornea 36:40-43
Eghrari, Allen O; Vahedi, Sina; Afshari, Natalie A et al. (2017) CTG18.1 Expansion in TCF4 Among African Americans With Fuchs' Corneal Dystrophy. Invest Ophthalmol Vis Sci 58:6046-6049
Eghrari, Allen O; Wang, Aaron; Brady, Christopher J (2017) GOOGLE CARDBOARD INDIRECT OPHTHALMOSCOPY. Retina 37:1617-1619
Eghrari, Allen O; Riazuddin, S Amer; Gottsch, John D (2016) Distinct Clinical Phenotype of Corneal Dystrophy Predicts the p.(Leu450Trp) Substitution in COL8A2. Cornea 35:587-91
Eghrari, Allen O; Riazuddin, S Amer; Gottsch, John D (2015) Overview of the Cornea: Structure, Function, and Development. Prog Mol Biol Transl Sci 134:7-23
Loprinzi, Paul D; Swenor, Bonnielin K; Ramulu, Pradeep Y (2015) Age-Related Macular Degeneration Is Associated with Less Physical Activity among US Adults: Cross-Sectional Study. PLoS One 10:e0125394
Vasanth, Shivakumar; Eghrari, Allen O; Gapsis, Briana C et al. (2015) Expansion of CTG18.1 Trinucleotide Repeat in TCF4 Is a Potent Driver of Fuchs' Corneal Dystrophy. Invest Ophthalmol Vis Sci 56:4531-6

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