This phase I study examines a DNA minor groove inhibitor, KW2189, in patients with relapsed gastric carcinoma. In a standard dose escalation study, toxicities of this agent in a heavily penetrated population of patients will be defined. To date, 6 patients have been treated at HUP. The MTD has not yet been reached.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
2M01RR000040-38A1
Application #
2783188
Study Section
Project Start
Project End
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
38
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
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