Pre and postmenopausal women are being fed varying concentrations of soy derived isoflavones. The relationship between the dose of isoflavones ingested and the amount of isoflavones and their bacterial metabolites excreted in the urine is being measured. The levels of isoflavones and their metabolites in the plasma are being measured and the relationship between the amount of isoflavones consumed and the urinary and plasma levels is being defined. In addition, the effect of isoflavones and their dose relationship to endogenous urinary and circulating estrogens is being determined.

Project Start
1999-12-01
Project End
2001-02-28
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
39
Fiscal Year
2000
Total Cost
$42,739
Indirect Cost
Name
Tufts University
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02111
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