This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.This study aims to evaluate if pre-treatment with hydrocortisone speeds the onset of response to Venlafaxine extended release (XR). In addition, we will evaluate if hydrocortisone pre-treatment augments Venlafaxine XR response. Patients will be treated with Venlafaxine for 6 weeks. Eligible patients will be admitted to the GCRC for 2 days, where they will be randomly assigned to receive either hydrocortisone or placebo intravenously during their stay in the hospital. Mood assessments, as well as neuropsychological tests of memory, will be completed at most visits.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
2M01RR000070-45
Application #
7605166
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2007-02-15
Project End
2007-11-30
Budget Start
2007-02-15
Budget End
2007-11-30
Support Year
45
Fiscal Year
2007
Total Cost
$2,340
Indirect Cost
Name
Stanford University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
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