Exposure to microgravity evokes complex physiological responses that contribute to muscular deconditioning and orthostatic intolerance. The effects of an oral branched chain amino acid solution on muscle protein turnover and fluid balance will be determined during 15-day head-down bedrest. Infusions of ring-13C-phenylalanine and muscle biopsies will determine muscle protein dynamics, while oral 15N-glycine will be utilized to determine whole-body protein turnover. Other body fluid and endocrine responses will also be measured.

Project Start
Project End
Budget Start
Budget End
Support Year
31
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Type
DUNS #
041367053
City
Galveston
State
TX
Country
United States
Zip Code
77555
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