This proposal is for continuation of the inpatient and outpatient Clinical Research Center for adults and children at the Shands Teaching Hospital of the J. Hillis Miller Health Center at the University of Florida. The Center is organized to enhance communication and collaboration in clinical investigative work among health scientists carrying out studies on the unit. These include specialists in gastroenterology, endocrinology, immunology, oncology, pathology, ophthalmology, psychology, pharmacology, pulmonary, nutrition, pharmacy, nephrology, cardiology, genetics and pediatrics. Research-oriented nursing and dietary staff assist the development of detailed protocols and assure adherence to them. The Program Director, Associate and Assistant Directors, assisted by the Advisory Committee, encourage and help young investigators develop clinical research proposals and basic investigative skills. A technician is responsible for dependable specimen handling and distribution and carries out assays for urine and blood constituents to assist investigators and save costs. The CRC enjoys the continuing strong commitment of support from the administrative leadership of the Health Center. A completely renovated 10 bed inpatient and outpatient facility was provided by Shands Hospital in October 1987. Since then, the Colleges of Medicine and Nursing have funded purchase of critical new equipment items for laboratory, patient care and administrative functions on the Center that enhances its capacity to serve as the focal point of clinical research at the University of Florida.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000082-38
Application #
6078236
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Program Officer
Wilde, David B
Project Start
1977-12-01
Project End
2001-11-30
Budget Start
1999-12-01
Budget End
2000-11-30
Support Year
38
Fiscal Year
2000
Total Cost
$1,856,725
Indirect Cost
Name
University of Florida
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Mangal, Naveen; James, Margaret O; Stacpoole, Peter W et al. (2018) Model Informed Dose Optimization of Dichloroacetate for the Treatment of Congenital Lactic Acidosis in Children. J Clin Pharmacol 58:212-220
Boissoneault, Jeff; Letzen, Janelle; Lai, Song et al. (2016) Abnormal resting state functional connectivity in patients with chronic fatigue syndrome: an arterial spin-labeling fMRI study. Magn Reson Imaging 34:603-8
Shumyak, Stepan; Yang, Li-Jun; Han, Shuhong et al. (2016) ""Lupoid hepatitis"" in SLE patients and mice with experimental lupus. Clin Immunol 172:65-71
Hendeles, Leslie; Khan, Yasmeen R; Shuster, Jonathan J et al. (2015) Omalizumab therapy for asthma patients with poor adherence to inhaled corticosteroid therapy. Ann Allergy Asthma Immunol 114:58-62.e2
Price, Catherine C; Levy, Shellie-Anne; Tanner, Jared et al. (2015) Orthopedic Surgery and Post-Operative Cognitive Decline in Idiopathic Parkinson's Disease: Considerations from a Pilot Study. J Parkinsons Dis 5:893-905
Krueger, Charlene A; Cave, Emily C; Garvan, Cynthia (2015) Fetal response to live and recorded maternal speech. Biol Res Nurs 17:112-20
Jones, Jacob D; Marsiske, Michael; Okun, Michael S et al. (2015) Latent growth-curve analysis reveals that worsening Parkinson's disease quality of life is driven by depression. Neuropsychology 29:603-9
Morishita, Takashi; Foote, Kelly D; Archer, Derek B et al. (2015) Smile without euphoria induced by deep brain stimulation: a case report. Neurocase 21:674-8
Del-Aguila, J L; Cooper-DeHoff, R M; Chapman, A B et al. (2015) Transethnic meta-analysis suggests genetic variation in the HEME pathway influences potassium response in patients treated with hydrochlorothiazide. Pharmacogenomics J 15:153-7
Del-Aguila, J L; Beitelshees, A L; Cooper-Dehoff, R M et al. (2014) Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. Pharmacogenomics J 14:35-40

Showing the most recent 10 out of 266 publications