This study is designed to monitor muscle metabolic (gas exchange, 31P MRS, venous metabolites, needle biopsy) responses to exercise: 1) to define the pathophysiology of muscle energy defects; 2) to assess the ability of exercise responses to predict the presence of energy defects as determined by muscle biochemical analysis; and 3) to monitor responses to treatment designed to improve energy availability in metabolic myopathies.

Project Start
Project End
Budget Start
Budget End
Support Year
24
Fiscal Year
1996
Total Cost
Indirect Cost
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