This study will: 1) determine the safety of Methotrexate (MTX) versus placebo in patients with osteoarthritis; 2) evaluate the efficacy of MTX versus placebo; 3) obtain information about the biologic effects of MTX on surrogate markers of tissue and cartilage damage present in osteoarthritic synovial fluid.

Project Start
1997-12-01
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
26
Fiscal Year
1998
Total Cost
Indirect Cost
City
Dallas
State
TX
Country
United States
Zip Code
75390
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