This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The purpose of this study is to compare blood and bronchoalveolar lavage fluid (BALF) anti-KLH (keyhole limpet hemocyanin) antibody isotype profiles and peripheral blood CD4+ T cell cytokine production after systemic or pulmonary exposure to KLH in patients with atopic asthma compared with healthy control subjects. This study will also determine if the anti-KLH antibody isotype and CD4 response to pulmonary or systemic KLH in asthmatics can be modulated by pretreatment with inhaled nedocromil or glucocorticosteroids (budesonide).

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000997-32
Application #
7606844
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2006-12-01
Project End
2007-11-30
Budget Start
2006-12-01
Budget End
2007-11-30
Support Year
32
Fiscal Year
2007
Total Cost
$62,155
Indirect Cost
Name
University of New Mexico
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
868853094
City
Albuquerque
State
NM
Country
United States
Zip Code
87131
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