The aim of this study is to learn more about the regulation of reproductive hormones in adult men, and specifically to determine whether it is testosterone (the main sex hormone produced by the testis) or estradiol (another sex hormone) which is more important in controlling the secretion of leutinizing hormone (LH) and follicle stimulating hormone (FSH) from the pituitary gland. To do this a medication will be administered which blocks the body's ability to convert testosterone to estradiol. Our hypothesis is that estradiol has a greater inhibitory effect on LH and FSH secretion than testosterone and that consequently blocking the production of estradiol will result in an increase in LH and FSH levels.

Project Start
1997-12-01
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
21
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
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