This is a Phase II trial of the marrow-purging reagent 4-hydroperoxycyclophosphamide, a cyclophosphamide congener that is activated upon contact with water. Patients are conditioned with busulfan and cyclophosphamide and receive autologous marrow that has been purged with 4-HC. We are examining rate of engraftment, disease-free survival and toxicity.

Project Start
Project End
Budget Start
Budget End
Support Year
9
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
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