Total parenteral nutrition (TPN) commonly leads to hepatic injury in neonates. The purpose of the current proposal is to determine if prophylactic treatment with TUDCA will prevent or reduce hepatic injury associated with TPN in neonates. This multicenter double-blind placebo- controlled trial was begun during the last year. Five subjects from our center and one from Dallas have been enrolled. Data is blinded so results are pending. Enrollment is continuing.

Project Start
1997-12-01
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
5
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
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