Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Bioqual, Inc.
United States
Zip Code
Robinson, R A; Burgess, W H; Emerson, S U et al. (1998) Structural characterization of recombinant hepatitis E virus ORF2 proteins in baculovirus-infected insect cells. Protein Expr Purif 12:75-84
Tsarev, S A; Tsareva, T S; Emerson, S U et al. (1997) Recombinant vaccine against hepatitis E: dose response and protection against heterologous challenge. Vaccine 15:1834-8
Cohen, J I; Moskal, T; Shapiro, M et al. (1996) Varicella in Chimpanzees. J Med Virol 50:289-92
Shaffer, D R; Emerson, S U; Murphy, P C et al. (1995) A hepatitis A virus deletion mutant which lacks the first pyrimidine-rich tract of the 5' nontranslated RNA remains virulent in primates after direct intrahepatic nucleic acid transfection. J Virol 69:6600-4
Mannucci, P M; Gdovin, S; Gringeri, A et al. (1994) Transmission of hepatitis A to patients with hemophilia by factor VIII concentrates treated with organic solvent and detergent to inactivate viruses. The Italian Collaborative Group. Ann Intern Med 120:1-7
Tsarev, S A; Tsareva, T S; Emerson, S U et al. (1994) Successful passive and active immunization of cynomolgus monkeys against hepatitis E. Proc Natl Acad Sci U S A 91:10198-202
Farci, P; Alter, H J; Wong, D C et al. (1994) Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization. Proc Natl Acad Sci U S A 91:7792-6
Ogata, N; Miller, R H; Ishak, K G et al. (1993) The complete nucleotide sequence of a pre-core mutant of hepatitis B virus implicated in fulminant hepatitis and its biological characterization in chimpanzees. Virology 194:263-76
Tsarev, S A; Emerson, S U; Reyes, G R et al. (1992) Characterization of a prototype strain of hepatitis E virus. Proc Natl Acad Sci U S A 89:559-63