The general objectives of the CAMAC are: (a) To provide the biostatistical support to better understand the nature history of HIV infection (b) To conduct the appropriate biostatistical analyses to determine the risk factors, and appropriate interventions to limit the spread of the disease and to (c) biostatistically help characterize any biologic or environmental factors which will alter the natural history of the disease (e.g., either limit or accelerate the morbidity and mortality associated with infection) in this population. The specific objectives of the CAMAC study are: (1) To provide the biostatistical support to study the natural history of HIV infection among a population of homosexual men who analyzing the demographic, socio-cultural and behavioral self-report data and by statistically correlating this data with physical examination findings, HIV antibody status, immunologic and blood chemistry and hematology parameters and the presence of antibodies to other viruses. (2) To statistically estimate the rate of disease progression of infection by comparing laboratory findings (HLA-type, CBC, SMA-12), immunologic parameters (by flow cytometry), physical examinations, neuropsychiatric evaluations and electromechanical findings (EEG, EKG, MRI, CAT, nerve conduction studies, radiographic findings) with behavioral events. (3) To statistically estimate the rate of seroconversion among sexually homosexual men as well as determine those behaviors which may alter the rate of seroconversion. (4) To statistically estimate the nature and extent of co-virus infections among sexually active homosexual men.

Project Start
1987-09-30
Project End
1995-09-29
Budget Start
1992-08-12
Budget End
1993-03-31
Support Year
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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