This contract is for the continued investigation of histocompatibility antigens unique to ethnic populations in the United States, with emphasis on Blacks and Native Americans. The contractor will screen sera from multiparous women to identify and acquire reagents capable of recognizing antigens unique to these populations. Even though much work has been done in this area over the past six years through previous contracts, there are still many individuals whose HLA typings are incomplete, placing them at a disadvantage when organ transplant is required. Full identification of the antigens of the MHC will lead to better matches for these populations, improving graft survival and reducing health care costs, much of which is federally subsidized.

Project Start
1988-07-29
Project End
1993-07-31
Budget Start
1989-03-17
Budget End
1991-07-31
Support Year
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Georgetown University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Yeager Jr, H; Rabin, D L; Stein, S R et al. (1999) Pulmonary sarcoidosis: comparison of patients at a university and a municipal hospital. J Natl Med Assoc 91:322-7