Abstract

To address one of the present needs of the Division of AIDS, the Efficacy Trials Branch (ETB) in the Vaccine and Prevention Research Program (VPRP) of the Division of AIDS, National Institute of Allergy and Infectious Diseases (NIAID), plans to continue to maintain a Statistical and Clinical Coordinating Center (SACCC) for providing: (1) statistical and research design expertise for the Women and Infants Transmission Study (WITS); (2) statistical analyses and data management for the WITS; (3) central coordination of the systems for laboratory specimen processing, storage, and retrieval supported by the ETB through existing contracts and subcontracts to keep track of the type and amount of specimens available in the national repository; (4) general statistical support for special projects of the ETB; and (5) educational and training activities involving statistical and data management issues for these studies. Specific responsibilities of the Contractor are described in the Work Statement.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research and Development Contracts (N01)
Project #
N01AI085339-004
Application #
6325512
Study Section
Project Start
1998-04-15
Project End
2003-04-14
Budget Start
2000-04-26
Budget End
2001-04-14
Support Year
Fiscal Year
2000
Total Cost
$1,141,015
Indirect Cost

  Institution

Name
Clinical Trials and Surveys Corporation
Department
Type
DUNS #
City
Owings Mills
State
MD
Country
United States
Zip Code
21117

  Publications

Paredes, Roger; Cheng, Irene; Kuritzkes, Daniel R et al. (2010) Postpartum antiretroviral drug resistance in HIV-1-infected women receiving pregnancy-limited antiretroviral therapy. AIDS 24:45-53
Ouyang, David W; Brogly, Susan B; Lu, Ming et al. (2010) Lack of increased hepatotoxicity in HIV-infected pregnant women receiving nevirapine compared with other antiretrovirals. AIDS 24:109-14
Mekmullica, Jutarat; Brouwers, Pim; Charurat, Manhattan et al. (2009) Early immunological predictors of neurodevelopmental outcomes in HIV-infected children. Clin Infect Dis 48:338-46
Watts, D H; Lu, M; Thompson, B et al. (2009) Treatment interruption after pregnancy: effects on disease progression and laboratory findings. Infect Dis Obstet Gynecol 2009:456717
Ouyang, David W; Shapiro, David E; Lu, Ming et al. (2009) Increased risk of hepatotoxicity in HIV-infected pregnant women receiving antiretroviral therapy independent of nevirapine exposure. AIDS 23:2425-30
Aldrovandi, Grace M; Chu, Clara; Shearer, William T et al. (2009) Antiretroviral exposure and lymphocyte mtDNA content among uninfected infants of HIV-1-infected women. Pediatrics 124:e1189-97
Dowd, Kimberly A; Hershow, Ronald C; Yawetz, Sigal et al. (2008) Maternal neutralizing antibody and transmission of hepatitis C virus to infants. J Infect Dis 198:1651-5
Pahwa, Savita; Read, Jennifer S; Yin, Wanrong et al. (2008) CD4+/CD8+ T cell ratio for diagnosis of HIV-1 infection in infants: Women and Infants Transmission Study. Pediatrics 122:331-9
Chen, Katherine T; Tuomala, Ruth E; Chu, Clara et al. (2008) No association between antepartum serologic and genital tract evidence of herpes simplex virus-2 coinfection and perinatal HIV-1 transmission. Am J Obstet Gynecol 198:399.e1-5
Mellins, C A; Chu, C; Malee, K et al. (2008) Adherence to antiretroviral treatment among pregnant and postpartum HIV-infected women. AIDS Care 20:958-68

Showing the most recent 10 out of 39 publications