The overall objective of this contract is to establish a population-based research registry for systemic sclerosis (scleroderma) in southeastern Michigan. The Contractor will identify all cases of systemic sclerosis, verify all diagnoses, establish a computer data base, provide a continuous update of the prevalence, incidence and mortality rates of scleroderma in this population, and establish prospectively the average annual mortality. As a major focus, the Contractor will establish a cohort of incident cases for early intervention trials, as well as for basic science and other clinical and epidemiological studies.
| Furspan, P B; Chatterjee, S; Mayes, M D et al. (2005) Cooling-induced contraction and protein tyrosine kinase activity of isolated arterioles in secondary Raynaud's phenomenon. Rheumatology (Oxford) 44:488-94 |
| Mayes, Maureen D; Lacey Jr, James V; Beebe-Dimmer, Jennifer et al. (2003) Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population. Arthritis Rheum 48:2246-55 |
| Mayes, Maureen D (2003) Scleroderma epidemiology. Rheum Dis Clin North Am 29:239-54 |
| Arnett, F C; Cho, M; Chatterjee, S et al. (2001) Familial occurrence frequencies and relative risks for systemic sclerosis (scleroderma) in three United States cohorts. Arthritis Rheum 44:1359-62 |
| Mayes, M D; Giannini, E H; Pachman, L M et al. (1997) Connective tissue disease registries. Arthritis Rheum 40:1556-9 |
