Abstract

Provide for performance of a prospective study to compare and evaluate the effects on two different oral contraceptive formulations and delivery of contraceptive steroids through the vaginal ring on plasma lipoprotein patterns and the occurrence of atherosclerosis in monkeys of the species Macaca Fascicularis.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research and Development Contracts (N01)
Project #
N01HD032800-004
Application #
3650516
Study Section
Project Start
1983-01-15
Project End
1986-07-14
Budget Start
1986-04-20
Budget End
1986-07-14
Support Year
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
Wake Forest University Health Sciences
Department
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106

  Publications

Adams, M R; Clarkson, T B; Shively, C A et al. (1990) Oral contraceptives, lipoproteins, and atherosclerosis. Am J Obstet Gynecol 163:1388-93
Shively, C A; Manuck, S B; Kaplan, J R et al. (1990) Oral contraceptive administration, interfemale relationships, and sexual behavior in Macaca fascicularis. Arch Sex Behav 19:101-17
Clarkson, T B; Adams, M R; Kaplan, J R et al. (1989) From menarche to menopause: coronary artery atherosclerosis and protection in cynomolgus monkeys. Am J Obstet Gynecol 160:1280-5