Objective: 1. To assess the safety and efficacy of initial trophic enteral feeding followed by advancement to full-calorie enteral feeding vs. initial advancement to full-calorie enteral feeding management strategies in reducing mortality and morbidity in patients with ALI or ARDS ? Hypotheses: 1. Initial trophic feeding followed by full-calorie enteral feeding will improve clinical outcomes (specifically increase the number of ventilator-free days to day 28 and decrease the 60-day, hospital mortality) in patients with ALI or ARDS by reducing systemic inflammation and the number of feeding complications as compared to early, full-calorie enteral feeding.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research and Development Contracts (N01)
Project #
N01HR56165-7-0-3
Application #
7824256
Study Section
Project Start
2005-09-30
Project End
2012-09-29
Budget Start
Budget End
Support Year
Fiscal Year
2009
Total Cost
$568,613
Indirect Cost
Name
Baystate Medical Center
Department
Type
DUNS #
079237988
City
Springfield
State
MA
Country
United States
Zip Code
01199