The Molecular Pathology Group (MPG) is a recent addition to the laboratory Animal Science Program (LASP), at the Frederick, Maryland campus of the National Cancer Institute (NCI). This SAIC-Frederick Inc group is actively working to expand high-quality, pathology-based research application support available to NCI investigators and their collaborators to further cancer research. Its primary role is to extend the capabilities of the existing SAIC-Frederick, Inc. Pathology and Histology Laboratory (PHL) core group by coordinating and performing advanced, tissue-based molecular imaging studies at the request of investigators. Currently MPG offers Nucleic acid isolation from fixed (archival) tissues coupled with appropriate integrity analysis / quality assessment and/or a pilot study (follow-on application). Additionally, tissue processing tailored to a specific follow on applications is available.